2-Fluoro-5-formylbenzonitrile

Base Information Edit

Chemical Name:2-Fluoro-5-formylbenzonitrile
CAS No.:218301-22-5
Molecular Formula:C8H4FNO
Molecular Weight:149.124
Hs Code.:29269090
European Community (EC) Number:628-221-3
DSSTox Substance ID:DTXSID30377772
Nikkaji Number:J1.276.334D
Wikidata:Q72458203
Mol file:218301-22-5.mol

Synonyms:2-Fluoro-5-formylbenzonitrile;218301-22-5;3-Cyano-4-fluorobenzaldehyde;4-Fluoro-3-cyanobenzaldehyde;BENZONITRILE, 2-FLUORO-5-FORMYL-;3-Cyano-4-fluoro benzaldehyde;MFCD01863558;2-fluoro-5-formyl-benzonitrile;fluoro-5-formylbenzonitrile;SCHEMBL48778;5-formyl-2-fluoro-benzonitrile;DTXSID30377772;MOFRJTLODZILCR-UHFFFAOYSA-N;BCP27987;CS-B0043;CL8320;STK503059;2-Fluoro-5-formylbenzonitrile, 97%;AKOS005171280;AC-4068;PS-8928;SY002652;2-fluoranyl-5-methanoyl-benzenecarbonitrile;22-fluoranyl-5-methanoyl-benzenecarbonitrile;A4675;AM20030361;BB 0253842;C2692;FT-0643997;EN300-112856;A815689;J-014309;J-515363;Z1255488904

Suppliers and Price of 2-Fluoro-5-formylbenzonitrile

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Cyano-4-fluorobenzaldehyde
10g
$ 950.00

TCI Chemical
3-Cyano-4-fluorobenzaldehyde >98.0%(GC)
1g
$ 41.00

TCI Chemical
3-Cyano-4-fluorobenzaldehyde >98.0%(GC)
5g
$ 121.00

SynQuest Laboratories
3-Cyano-4-fluorobenzaldehyde 98%
25 g
$ 75.00

SynQuest Laboratories
3-Cyano-4-fluorobenzaldehyde 98%
5 g
$ 25.00

SynQuest Laboratories
3-Cyano-4-fluorobenzaldehyde 98%
100 g
$ 200.00

Sigma-Aldrich
2-Fluoro-5-formylbenzonitrile 97%
5g
$ 230.00

Oakwood
3-Cyano-4-fluorobenzaldehyde 98%
5g
$ 17.00

Oakwood
3-Cyano-4-fluorobenzaldehyde 98%
1g
$ 10.00

Medical Isotopes, Inc.
3-Cyano-4-fluorobenzaldehyde
1 g
$ 620.00

Total 144 raw suppliers

Chemical Property of 2-Fluoro-5-formylbenzonitrile Edit

Chemical Property:

Melting Point:80-84 °C(lit.)
Boiling Point:215.603 °C at 760 mmHg
Flash Point:84.194 °C
PSA：40.86000
Density:1.26 g/cm³
LogP:1.50988
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:Chloroform, Methanol
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:149.027691913
Heavy Atom Count:11
Complexity:196

Purity/Quality:

99.5%+ ^*data from raw suppliers

3-Cyano-4-fluorobenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C=O)C#N)F
Uses 2-Fluoro-5-ForMyl-benzonitrile is used in the preparation of heterocyclic compounds as PARP inhibitors for medical use. 2-Fluoro-5-formylbenzonitrile may be used in the synthesis of 3-cyano-4-fluorobenzyl bromide.

Technology Process of 2-Fluoro-5-formylbenzonitrile

There total 8 articles about 2-Fluoro-5-formylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: copper(l) cyanide

: 77771-02-9
3-bromo-4-fluorobenzaldehyde

: 218301-22-5
2-fluoro-5-formylbenzonitrile

Guidance literature:: copper(l) cyanide; 3-bromo-4-fluorobenzaldehyde; In 1-methyl-pyrrolidin-2-one; at 170 ℃; for 24h;

With celite; In 1-methyl-pyrrolidin-2-one; at 80 ℃; for 1h;