(2R,3R)-2-Amino-3-methyloxybutanoic acid

Base Information

• Chemical Name: (2R,3R)-2-Amino-3-methyloxybutanoic acid
• CAS No.: 104195-79-1
• Molecular Formula: C₅H₁₁NO₃
• Molecular Weight: 133.147
• Hs Code.: 2922509090
• Mol file: 104195-79-1.mol

Synonyms:(2R,3R)-2-Amino-3-methyloxybutanoic acid

Chemical Property of (2R,3R)-2-Amino-3-methyloxybutanoic acid

Chemical Property:

• Refractive Index: 1.461
• Boiling Point: 1.143 g/cm³
• PKA: 2.12±0.10(Predicted)
• Flash Point: 103.8 °C
• PSA: 72.55000
• Density: 1.143 g/cm³
• LogP: 0.13350

Purity/Quality:

98%Min ^*data from raw suppliers

ALLO-O-METHYL-D-THR 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R,3R)-2-Amino-3-methyloxybutanoic acid

There total 7 articles about (2R,3R)-2-Amino-3-methyloxybutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-Trt-Thr (85918-01-0,115201-03-1) → O-methyl-L-threonine (2076-53-1,2076-57-5,4144-02-9,4385-90-4,34223-42-2,88642-93-7,104195-79-1,104195-80-4)

Guidance literature:

With acetic acid; In ethanol; for 24h; Ambient temperature;

DOI:10.1016/S0040-4020(01)88549-5

Reference yield:

→ 2-Amino-3-methoxybutanoic acid (2076-53-1,2076-57-5,4144-02-9,4385-90-4,34223-42-2,88642-93-7,104195-79-1,104195-80-4)

Guidance literature:

3-Methoxy-2-nitro-buttersaeure, MeOH, H2, Pt;

Reference yield:

N-formyl-O-methyl-DL-allothreonine (6622-23-7,7153-82-4,7505-36-4,44975-87-3) → O-methyl-DL-allothreonine (2076-53-1,2076-57-5,4144-02-9,4385-90-4,34223-42-2,88642-93-7,104195-79-1,104195-80-4)

Guidance literature:

With hydrogen bromide;

upstream raw materials:

N-formyl-O-methyl-DL-allothreonine

O-methyl-N-benzoyl-DL-allothreonine

N-formyl-O-methyl-DL-threonine

O-methyl-N-benzoyl-DL-threonine

Downstream raw materials:

C₇H₁₃NO₅

N-formyl-O-methyl-DL-allothreonine

O-methyl-N-benzoyl-DL-allothreonine

(+/-)-erythro-2-bromo-3-methoxy-butyric acid anilide

Refernces