4,5-Dibromo-1,2-benzenediol

Base Information

• Chemical Name: 4,5-Dibromo-1,2-benzenediol
• CAS No.: 2563-26-0
• Molecular Formula: C6H4Br2O2
• Molecular Weight: 267.905
• Hs Code.: 2908199090
• Mol file: 2563-26-0.mol

Synonyms:Pyrocatechol, 4,5-dibromo- (6CI,7CI);4,5-Dibromo-1,2-benzenediol;4,5-Dibromocatechol;4,5-Dibromopyrocatechol;NSC10858;

Chemical Property of 4,5-Dibromo-1,2-benzenediol

Chemical Property:

• Vapor Pressure: 9.89E-05mmHg at 25°C
• Melting Point: 111-116°C (lit.)
• Refractive Index: 1.69
• Boiling Point: 328.5 °C at 760 mmHg
• PKA: 7.98±0.23(Predicted)
• Flash Point: 152.5 °C
• PSA: 40.46000
• Density: 2.257g/cm³
• LogP: 2.62280
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

4,?5-?Dibromobenzene-?1,?2-?diol(90%,technicalgrade) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4,?5-?Dibromobenzene-?1,?2-?diol is a dye. Dyes and metabolites.

Technology Process of 4,5-Dibromo-1,2-benzenediol

There total 10 articles about 4,5-Dibromo-1,2-benzenediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2-dibromo-4,5-dimethoxybenzene (37895-73-1) → 4,5-dibromobenzene-1,2-diol (2563-26-0)

Guidance literature:

With boron tribromide; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1002/anie.200603945

Reference yield: 91.0%

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 4,5-dibromobenzene-1,2-diol (2563-26-0)

Guidance literature:

With bromine; In tetrachloromethane; for 16h; from 0 deg C to r.t.;

Reference yield:

chloroform (67-66-3,8013-54-5) + bromine (7726-95-6) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → Tetrabromocatechol (488-47-1) + 4,5-dibromobenzene-1,2-diol (2563-26-0) + 3,4,5-tribromocatechol (2747-17-3)

Guidance literature:

DOI:10.1021/ja01145a519

upstream raw materials:

5,6-dibromo-2,2-dimethyl-benzo[1,3]dioxole

benzene-1,2-diol

1,2-dibromo-4,5-dimethoxybenzene

bromine

Downstream raw materials:

1,2-Dibromo-4,5-bis(pentyloxy)benzene

4,5-dibromo-1,2-bis(tetradecyloxy)benzene

1,2-dibromo-4',5'-di-n-dodecyloxybenzene

1,2-Dibromo-4,5-bis-octadecyloxy-benzene

Refernces

• 1、 Tian, Jing,Jing, Lu,Ji, Lisha,Zhang, Congcong,Liu, Qingyun,Zhang, Xiaomei. "Helical self-assembly and nonlinear optical properties of optically active phthalocyanine derivatives bearing eight optically active diethyleneglycol mono-(S)-2-methylbutyl ether moieties on the β-position of the phthalocyanine ring". . p. 22461 - 22468. Retrieved 2013.
• 2、 -. "Synthesis of phenylethynylbenzenes". Page/Page column 11. . Retrieved 2018/06/08.
• 3、 Cidlina, Antonin,Svec, Jan,Ludvová, Lucie,Kune?, Ji?í,Zimcik, Petr,Novakova, Veronika. "Predominant effect of connecting atom and position of substituents on azomethine nitrogens' basicity in phthalocyanines". . p. 1122 - 1133. Retrieved 2016/12/16.