1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose

Base Information Edit

Chemical Name:1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose
CAS No.:3601-89-6
Molecular Formula:C21H21ClO5
Molecular Weight:388.848
Hs Code.:
Mol file:3601-89-6.mol

Synonyms:D-erythro-Pentofuranosylchloride, 2-deoxy-, bis(4-methylbenzoate) (9CI);D-erythro-Pentofuranosylchloride, 2-deoxy-, di-p-toluate (7CI,8CI);Ribofuranosyl chloride, 2-deoxy-,di-p-toluate, D- (6CI);2-Deoxy-3,5-di-O-p-toluoyl-D-erythro-pentofuranosylchloride;3,5-Di-O-p-toluoyl-2-deoxy-D-ribofuranosyl chloride;

Suppliers and Price of 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride
200mg
$ 312.00

TRC
2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosylChloride
1g
$ 70.00

TRC
2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosylChloride
200mg
$ 55.00

TRC
2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosylChloride
25g
$ 1335.00

Sigma-Aldrich
3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride ~90%
1 g
$ 904.00

Medical Isotopes, Inc.
2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosylchloride
5 g
$ 290.00

Crysdot
(2R,3S)-5-Chloro-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl4-methylbenzoate 90%
25g
$ 350.00

Crysdot
(2R,3S)-5-Chloro-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl4-methylbenzoate 90%
10g
$ 200.00

Crysdot
(2R,3S)-5-Chloro-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl4-methylbenzoate 90%
1g
$ 55.00

Crysdot
(2R,3S)-5-Chloro-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl4-methylbenzoate 90%
5g
$ 110.00

Total 118 raw suppliers

Chemical Property of 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose Edit

Chemical Property:

Appearance/Colour:Crystalline solid
Melting Point:109 °C dec.
Refractive Index:1.581
Boiling Point:518.4 °C at 760 mmHg
Flash Point:185.6 °C
PSA：61.83000
Density:1.283 g/cm³
LogP:4.03960
Storage Temp.:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility.:Acetonitrile (Slightly), Chloroform (Slightly), Dichloromethane (Slightly), DMSO

Purity/Quality:

99% ^*data from raw suppliers

2-Deoxy-3,5-di-O-p-toluoyl-D-ribofuranosyl Chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose is a versatile carbohydrate derivative univerisally used for the preparation of 2 deoxynucleosides.

Technology Process of 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose

There total 12 articles about 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 452-51-7,13046-70-3,29780-54-9,36792-87-7,36792-88-8,113890-35-0,113890-38-3
D-2-deoxyribose

: 874-60-2
4-methyl-benzoyl chloride

: 3601-89-6,4330-21-6,52304-86-6,3056-12-0,141846-57-3
Hoffer's chlorosugar

Guidance literature:: D-2-deoxyribose; With acetyl chloride; In methanol; at 20 ℃; for 1h;

4-methyl-benzoyl chloride; With pyridine; dmap; at 20 ℃; Cooling with ice;

Reference yield: 63.0%

: 452-51-7,13046-70-3,29780-54-9,36792-87-7,36792-88-8,113890-35-0,113890-38-3
D-2-deoxyribose

: 874-60-2
4-methyl-benzoyl chloride

: 3056-12-0,3601-89-6,4330-21-6,52304-86-6,141846-57-3
2-deoxy-3,5-di-O-(p-toluoyl)-α-D-erythropentofuranosyl chloride

Guidance literature:: D-2-deoxyribose; With acetyl chloride; In methanol; for 0.75h; Inert atmosphere;

4-methyl-benzoyl chloride; With pyridine; dmap; In methanol; at 0 - 20 ℃; Inert atmosphere;