2,3-Difluoro-4-iodophenol

Base Information

• Chemical Name: 2,3-Difluoro-4-iodophenol
• CAS No.: 144292-40-0
• Molecular Formula: C6H3F2IO
• Molecular Weight: 255.991
• Hs Code.: 2908199090
• Mol file: 144292-40-0.mol

Synonyms:4-Iodo-2,3-difluorophenol;

Chemical Property of 2,3-Difluoro-4-iodophenol

Chemical Property:

• Vapor Pressure: 0.0163mmHg at 25°C
• Refractive Index: 1.609
• Boiling Point: 247.455 °C at 760 mmHg
• Flash Point: 103.457 °C
• PSA: 20.23000
• Density: 2.163 g/cm³
• LogP: 2.27500
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

2,3-Difluoro-4-iodophenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-Difluoro-4-iodophenol

There total 2 articles about 2,3-Difluoro-4-iodophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4N-hydrochloric acid + 2,3-difluorophenol (6418-38-8) → 2,3-difluoro-4-iodophenol (144292-40-0)

Guidance literature:

With sodium hydroxide; sodium hypochlorite; sodium iodide; sodium thiosulfate; In methanol;

Reference yield:

2,3-difluorophenol (6418-38-8) → 2,3-difluoro-4-iodophenol (144292-40-0)

Guidance literature:

With sodium hydroxide; sodium hypochlorite; sodium iodide; sodium thiosulfate; In methanol;

Reference yield: 63.6%

2,3-difluoro-4-iodophenol (144292-40-0) + (2S,4S)-N-tert-butoxycarbonyl-4-hydroxyproline methyl ester (74844-91-0,114676-69-6,135042-17-0,227935-38-8,102195-79-9) → (2S,4R)-1-tert-butyl 2-methyl 4-(2,3-difluoro-4-iodophenoxy)pyrrolidine-1,2-dicarboxylate

Guidance literature:

2,3-difluoro-4-iodophenol; (2S,4S)-N-tert-butoxycarbonyl-4-hydroxyproline methyl ester; With triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

With di-isopropyl azodicarboxylate; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

upstream raw materials:

2,3-difluorophenol

Downstream raw materials:

C₁₅H₁₆F₂INO₂S

Refernces

• 1、 -. "Liquid crystal compounds and compositions". . . Retrieved 2008/06/13.