Fmoc-4-nitro-L-phenylalanine

Base Information Edit

Chemical Name:Fmoc-4-nitro-L-phenylalanine
CAS No.:95753-55-2
Molecular Formula:C24H20N2O6
Molecular Weight:432.433
Hs Code.:2924 29 70
European Community (EC) Number:688-912-0
DSSTox Substance ID:DTXSID10426792
Nikkaji Number:J1.690.279I
Wikidata:Q72478731
Mol file:95753-55-2.mol

Synonyms:95753-55-2;Fmoc-4-nitro-L-phenylalanine;Fmoc-Phe(4-NO2)-OH;Fmoc-L-4-Nitrophe;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-nitrophenyl)propanoic acid;(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-nitrophenyl)propanoic acid;fmoc-p-nitro-phe-oh;N-Fmoc-4-nitro-L-phenylalanine;Fmoc-L-4-NO2-Phe-OH;Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-nitro-;MFCD00057810;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-nitro-L-phenylalanine;fmoc-4-nitrophenylalanine;N-Fmoc-4-Nitro-L-Phe-OH;SCHEMBL800312;DTXSID10426792;AKOS015837264;AC-9941;AC-9942;AM83458;CS-W011622;HY-W010906;(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-nitrophenyl)propanoic acid;PS-12015;F0443;EN300-312406;M03192;S12017;Fmoc-4-Nitro-phenylalanine Fmoc-Phe(4-NO2)-OH;Fmoc-Phe(4-NO2)-OH, >=96.0% (HPLC);A845456;J-300425;Z2044796602;(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-nitrophenyl)propanoic acid;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-nitro-L-phenylalanine (Fmoc-L-Phe(4-NO2)-OH)

Suppliers and Price of Fmoc-4-nitro-L-phenylalanine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-4-nitro-L-phenylalanine 99+%
1g
$ 163.00

TRC
Fmoc-Phe(4-NO2)-OH
25g
$ 745.00

TRC
Fmoc-Phe(4-NO2)-OH
5g
$ 230.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-nitro-L-phenylalanine >98.0%(HPLC)(T)
5g
$ 81.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-nitro-L-phenylalanine >98.0%(HPLC)(T)
1g
$ 27.00

Sigma-Aldrich
Fmoc-Phe(4-NO?)-OH Novabiochem?
1 g
$ 36.80

Sigma-Aldrich
Fmoc-Phe(4-NO?)-OH Novabiochem?
5 g
$ 141.00

Sigma-Aldrich
Fmoc-Phe(4-NO)-OHFmoc-Phe(4-NO )-OH Novabiochem . CAS 95753-55-2, molar mass 432.43 g/mol., Novabiochem
8520290005
$ 136.00

Sigma-Aldrich
Fmoc-Phe(4-NO)-OHFmoc-Phe(4-NO )-OH Novabiochem . CAS 95753-55-2, molar mass 432.43 g/mol., Novabiochem
8520290001
$ 35.50

Sigma-Aldrich
Fmoc-Phe(4-NO2)-OH ≥96.0% (HPLC)
5g
$ 174.00

Total 68 raw suppliers

Chemical Property of Fmoc-4-nitro-L-phenylalanine Edit

Chemical Property:

Melting Point:213-223℃
Boiling Point:692.3 °C at 760 mmHg
PKA:3.59±0.10(Predicted)
Flash Point:372.5 °C
PSA：121.45000
Density:1.371 g/cm³
LogP:5.04330
Storage Temp.:2-8°C
Solubility.:almost transparency in N,N-DMF
XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:432.13213636
Heavy Atom Count:32
Complexity:665

Purity/Quality:

98% ^*data from raw suppliers

Fmoc-4-nitro-L-phenylalanine 99+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC=C(C=C4)[N+](=O)[O-])C(=O)O
Isomeric SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC4=CC=C(C=C4)[N+](=O)[O-])C(=O)O
Uses Fmoc-Phe(4-NO2)-OH is used to prepare squaric acid derivatives as VLA-4 integrin antagonists. It is also an intermediate used in the synthesis of analogs of kahalalide F.

Technology Process of Fmoc-4-nitro-L-phenylalanine

There total 4 articles about Fmoc-4-nitro-L-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%