cis-4-Propylcyclohexanol

Base Information

• Chemical Name: cis-4-Propylcyclohexanol
• CAS No.: 98790-22-8
• Molecular Formula: C₉H₁₈O
• Molecular Weight: 142.241
• Mol file: 98790-22-8.mol

Synonyms:cis-4-Propylcyclohexanol

Chemical Property of cis-4-Propylcyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-4-Propylcyclohexanol

There total 17 articles about cis-4-Propylcyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.5%

4-propyl-cyclohexanone (40649-36-3) → cis-4-Propylcyclohexanol (98790-22-8)

Guidance literature:

With NADH; In aq. phosphate buffer; water; isopropyl alcohol; at 235 ℃; for 27h; pH=7.5; Reagent/catalyst; Microbiological reaction;

DOI:10.1021/op049961e

Reference yield: 59.0%

4-n-Propylphenol (645-56-7) → 4-propyl-cyclohexanone (40649-36-3) + trans-4-propylcyclohexanol (77866-58-1) + cis-4-Propylcyclohexanol (98790-22-8)

Guidance literature:

With chloro(1,5-hexadiene)rhodium(I) dimer; hydrogen; tetra(n-butyl)ammonium hydrogensulfate; boric acid; sodium phosphate; citric acid; In hexane; for 50h; under 760 Torr; Ambient temperature;

DOI:10.1139/v97-149

Reference yield:

ethanol (64-17-5) + 2-methoxy-4-n-propylphenol (2785-87-7) → 2-methoxy-4-propylcyclohexane-1-ol (23950-98-3) + trans-4-propylcyclohexanol (77866-58-1) + cis-4-Propylcyclohexanol (98790-22-8)

Guidance literature:

at 150 - 160 ℃; Hydrogenation;

upstream raw materials:

Estragole

2-methoxy-4-n-propylphenol

anethole

4-propyl-cyclohexanone

Downstream raw materials:

trans-2-(4-propylcyclohexyl)-1,3-propanediol

trans-4-propylcyclohexanol

4-propyl-cyclohexanone

Refernces

• 1、 Nagasawa, Yoshiyuki,Hiraishi, Yushi,Horyo, Daiki,Sobu, Tomoki,Taniguchi, Kenkichi,Nanao, Hidetaka,Sato, Osamu,Yamaguchi, Aritomo,Shirai, Masayuki. "Hydrogenation of 4-propylphenol over carbon-supported palladium catalyst without external hydrogen: Effect of carbon support and palladium loading". . p. 431 - 434. Retrieved 2021/03/15.
• 2、 Ikunaka, Masaya,Moriya, Narimasa,Nomoto, Fumiki,Ohsako, Akihiro,Okuda, Yoshiaki,Suenaga, Hitoshi. "The highly selective equatorial hydride delivery by biocatalysis: Chemoenzymatic synthesis of trans-2-(4-propylcyclohexyl)-1,3-propanediol via cis-4-propylcyclohexanol". . p. 389 - 395. Retrieved 2013/09/05.