N,N'-dibenzylethylenediamine rosuvastatin

Base Information

• Chemical Name: N,N'-dibenzylethylenediamine rosuvastatin
• CAS No.: 1045601-12-4
• Molecular Formula: C₁₆H₂₀N₂*C₂₂H₂₈FN₃O₆S
• Molecular Weight: 721.893
• Mol file: 1045601-12-4.mol

Synonyms:N,N'-dibenzylethylenediamine rosuvastatin

Chemical Property of N,N'-dibenzylethylenediamine rosuvastatin

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N,N'-dibenzylethylenediamine rosuvastatin

There total 1 articles about N,N'-dibenzylethylenediamine rosuvastatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rosuvastatin tert-butyl ester (355806-00-7) + N,N'-dibenzylethylenediamine diacetate (122-75-8) → N,N'-dibenzylethylenediamine rosuvastatin (1045601-12-4)

Guidance literature:

rosuvastatin tert-butyl ester; With sodium hydroxide; In ethanol; water; at 25 - 30 ℃; for 1h;

N,N'-dibenzylethylenediamine diacetate; In water; for 2h;

Reference yield:

N,N'-dibenzylethylenediamine rosuvastatin (1045601-12-4) → crestor

Guidance literature:

N,N'-dibenzylethylenediamine rosuvastatin; With hydrogenchloride; In water; ethyl acetate; at 0 - 5 ℃;

With sodium hydroxide; In water; ethyl acetate; at 0 - 20 ℃;

With calcium chloride; In water; Product distribution / selectivity;

upstream raw materials:

rosuvastatin tert-butyl ester

N,N'-dibenzylethylenediamine diacetate

Refernces