Technology Process of rac-2-azido-1-(4-fluorophenyl)ethanol
There total 4 articles about rac-2-azido-1-(4-fluorophenyl)ethanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
para-fluorostyrene;
With
trimethylsilylazide; 9-(2-mesityl)-10-methylacridinium perchlorate;
In
toluene;
at 20 ℃;
for 12h;
Irradiation;
With
hydrogenchloride; triphenylphosphine;
In
water; acetonitrile;
at 20 ℃;
for 0.5h;
DOI:10.1021/acscatal.7b02892
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium azide; potassium iodide / water; acetonitrile / 1 h / 60 °C / Green chemistry
2: sodium tetrahydroborate / methanol / 1.25 h / 5 - 20 °C / Green chemistry
With
sodium tetrahydroborate; sodium azide; potassium iodide;
In
methanol; water; acetonitrile;
DOI:10.1039/c3gc41666f
- Guidance literature:
-
Multi-step reaction with 2 steps
1: azide on Amberlite(R) IRA 900 / CH2Cl2 / 0.5 h / 30 °C
2: borohydride on Amberlite(R) IRA 900 / methanol / 0.5 h / 30 °C
With
azide on Amberlite(R) IRA 900; borohydride on Amberlite(R) IRA 900;
In
methanol; dichloromethane;
DOI:10.1016/j.tetlet.2005.05.023
