Technology Process of benzyl 3,4,6-tri-O-benzyl-2-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside
There total 8 articles about benzyl 3,4,6-tri-O-benzyl-2-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
benzyl 2-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranoside;
With
sodium methylate;
In
methanol;
at 20 ℃;
for 3h;
Inert atmosphere;
In
methanol;
for 0.166667h;
Inert atmosphere;
DOI:10.1039/c1cc12981c
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) NaOMe, 2.) NaH / 1.) MeOH
2: 92 g / HgBr2 / 9 h / 140 °C
3: 55 g / NaOMe / tetrahydrofuran; methanol / 4 h / 15 - 20 °C
4: 85 percent / molecular sieves 4 Angstroem, AgOSO2CF3 / 1,2-dichloro-ethane / 1.) -30 deg C; 2.) 20 deg C, 1 h
5: 76 percent / NaOMe / tetrahydrofuran; methanol / 2 h / 20 °C
With
4 A molecular sieve; sodium methylate; silver trifluoromethanesulfonate; sodium hydride; mercury dibromide;
sodium methylate;
In
tetrahydrofuran; methanol; 1,2-dichloro-ethane;
DOI:10.1016/S0008-6215(00)82588-4
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 85 percent / molecular sieves 4 Angstroem, AgOSO2CF3 / 1,2-dichloro-ethane / 1.) -30 deg C; 2.) 20 deg C, 1 h
2: 76 percent / NaOMe / tetrahydrofuran; methanol / 2 h / 20 °C
With
4 A molecular sieve; silver trifluoromethanesulfonate;
sodium methylate;
In
tetrahydrofuran; methanol; 1,2-dichloro-ethane;
DOI:10.1016/S0008-6215(00)82588-4
