Tert-butyl N-[4-(aminomethyl)phenyl]carbamate

Base Information Edit

Chemical Name:Tert-butyl N-[4-(aminomethyl)phenyl]carbamate
CAS No.:220298-96-4
Molecular Formula:C12H18N2O2
Molecular Weight:222.287
Hs Code.:2924299090
European Community (EC) Number:672-196-1
DSSTox Substance ID:DTXSID60383301
Nikkaji Number:J1.604.035E
Wikidata:Q72510805
Mol file:220298-96-4.mol

Synonyms:220298-96-4;Tert-butyl N-[4-(aminomethyl)phenyl]carbamate;4-(BOC-AMINO)BENZYLAMINE;4-(Aminomethyl)-1-N-Boc-aniline;tert-Butyl (4-(aminomethyl)phenyl)carbamate;4-(tert-butoxycarbonylamino)benzylamine;MFCD02183573;tert-Butyl [4-(aminomethyl)phenyl]carbamate;(4-aminomethyl-phenyl)-carbamic acid tert-butyl ester;Carbamic acid, [4-(aminomethyl)phenyl]-, 1,1-dimethylethyl ester;tert-butyl-N-[4-(aminomethyl)phenyl]carbamate;4-(N-Boc-Amino)benzylamine;4-Aminomethyl-N-Boc-aniline;4-BOC-aminobenzylamine;SCHEMBL34480;4-(Aminomethyl)-N-Boc-aniline;DTXSID60383301;4-(Boc-amino)benzylamine, 95%;URXUHALBOWYXJZ-UHFFFAOYSA-N;4-(aminomethyl)-N-Boc-benzenamine;AKOS000169382;AC-6311;CS-W002926;SB80248;4-(tert-Butoxycarbonylamino)-benzylamine;AS-38354;SY006103;tert-butyl 4-(aminomethyl)phenylcarbamate;A4736;FT-0644026;EN300-83780;N-(tert-Butyloxycarbonyl)-4-(aminomethyl)aniline;J-514432

Suppliers and Price of Tert-butyl N-[4-(aminomethyl)phenyl]carbamate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Boc-amino)benzylamine
5g
$ 700.00

SynQuest Laboratories
4-Aminobenzylamine, 4-Boc protected
5 g
$ 570.00

SynQuest Laboratories
4-Aminobenzylamine, 4-Boc protected
1 g
$ 148.00

SynQuest Laboratories
4-Aminobenzylamine, 4-Boc protected
250 mg
$ 48.00

Sigma-Aldrich
4-(Boc-amino)benzylamine 95%
500mg
$ 77.90

Oakwood
4-(Aminomethyl)-1-N-Boc-aniline
5g
$ 278.00

Oakwood
4-(Aminomethyl)-1-N-Boc-aniline
10g
$ 433.00

Oakwood
4-(Aminomethyl)-1-N-Boc-aniline
250mg
$ 30.00

Oakwood
4-(Aminomethyl)-1-N-Boc-aniline
1g
$ 75.00

Matrix Scientific
4-(tert-Butoxycarbonylamino)benzylamine
500mg
$ 75.00

Total 44 raw suppliers

Chemical Property of Tert-butyl N-[4-(aminomethyl)phenyl]carbamate Edit

Chemical Property:

Vapor Pressure:0.00114mmHg at 25°C
Melting Point:64-68 °C(lit.)
Refractive Index:1.564
Boiling Point:300.1 °C at 760 mmHg
PKA:13.68±0.70(Predicted)
Flash Point:135.3 °C
PSA：64.35000
Density:1.12 g/cm³
LogP:3.26560
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:222.136827821
Heavy Atom Count:16
Complexity:228

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(Boc-amino)benzylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, C
Hazard Codes:Xi,C,Xn
Statements: 36/37/38-34-22-43
Safety Statements: 26-36-45-36/37/39-22-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC=C(C=C1)CN
Uses 4-(Boc-amino)benzylamine is used in preparation of degradation agents for Cyclin dependent kinase useful for the treatment of cancer.

Technology Process of Tert-butyl N-[4-(aminomethyl)phenyl]carbamate

There total 12 articles about Tert-butyl N-[4-(aminomethyl)phenyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%