1,1,2,2-Tetrafluoro-3-iodopropane

Base Information

• Chemical Name: 1,1,2,2-Tetrafluoro-3-iodopropane
• CAS No.: 679-87-8
• Molecular Formula: C3H3 F4 I
• Molecular Weight: 241.955
• Hs Code.: 29037990
• European Community (EC) Number: 626-510-9
• DSSTox Substance ID: DTXSID40337468
• Nikkaji Number: J128.990J
• Wikidata: Q72505240
• Mol file: 679-87-8.mol

Synonyms:679-87-8;1,1,2,2-Tetrafluoro-3-iodopropane;1-Iodo-2,2,3,3-tetrafluoropropane;2,2,3,3-tetrafluoropropyl iodide;1h,1h,3h-tetrafluoropropyl iodide;Propane, 1,1,2,2-tetrafluoro-3-iodo-;1,1,2,2-tetrafluoro-3-iodo-propane;SCHEMBL507191;2,2,3,3-Tetrafluorpropyljodid;DTXSID40337468;2,2,3,3-tetrafluoro-1-iodopropane;MFCD00019033;AKOS005259210;1,1,2,2-Tetrafluoro-3-iodo propane;FS-3870;1,1,2,2-Tetrafluoro-3-iodopropane, 98%;CS-0239081;FT-0609084;EN300-205314;1,1,2,2-tetrakis(fluoranyl)-3-iodanyl-propane;A835955

Chemical Property of 1,1,2,2-Tetrafluoro-3-iodopropane

Chemical Property:

• Vapor Pressure: 44.2mmHg at 25°C
• Refractive Index: n20/D 1.414(lit.)
• Boiling Point: 99.3 °C at 760 mmHg
• Flash Point: 29.4 °C
• PSA: 0.00000
• Density: 2.117
• LogP: 2.32180
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 241.92156
• Heavy Atom Count: 8
• Complexity: 71.7

Purity/Quality:

98%min ^*data from raw suppliers

3-Iodo-1,1,2,2-tetrafluoropropane 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(F)F)(F)F)I

Technology Process of 1,1,2,2-Tetrafluoro-3-iodopropane

There total 4 articles about 1,1,2,2-Tetrafluoro-3-iodopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1,1,3-trihydroperfluoropropyl benzenesulfonate (65675-12-9) → 1-iodo-1,1,3-trihydroperfluoropropane (679-87-8)

Guidance literature:

With potassium iodide; In N,N-dimethyl-formamide; Heating;

Reference yield:

p-toluenesulfonic acid-2,2,3,3-tetrafluoropropyl ester (786-31-2) → 1-iodo-1,1,3-trihydroperfluoropropane (679-87-8)

Guidance literature:

With potassium iodide; In diethylene glycol; at 170 ℃;

DOI:10.1007/BF00909446

Reference yield:

tris(2,2,3,3-tetrafluoropropyl)phosphite (2241-68-1) → 1-iodo-1,1,3-trihydroperfluoropropane (679-87-8)

Guidance literature:

With methyl iodide; at 220 - 230 ℃; for 4h;

DOI:10.1007/BF00925414

upstream raw materials:

p-toluenesulfonic acid-2,2,3,3-tetrafluoropropyl ester

tris(2,2,3,3-tetrafluoropropyl)phosphite

1,1,3-trihydroperfluoropropyl benzenesulfonate

Downstream raw materials:

1,1,2,2-Tetrafluorpropan

3-(2,2,3,3-tetrafluoropropoxy)benzaldehyde

4-methyl-5-[(2,2,3,3-tetrafluoropropylthio)(2,3,6-trifluorophenyl)methyl]pyridine-2-carboxamide

4-methyl-5-[(2,3,6-trifluorophenyl)methyl]pyridine-2-carboxamide

Refernces

• 1、 Konno, Tsutomu,Chae, Jungha,Kanda, Masashi,Nagai, Go,Tamura, Kazushige,Ishihara, Takashi,Yamanaka, Hiroki. "Facile syntheses of various per- or polyfluoroalkylated internal acetylene derivatives". . p. 7571 - 7580. Retrieved 2007/10/03.