Tdbtu

Base Information

• Chemical Name: Tdbtu
• CAS No.: 125700-69-8
• Molecular Formula: C12H16N5O2^.BF4
• Molecular Weight: 349.09
• Hs Code.: 29339900
• European Community (EC) Number: 675-206-2
• DSSTox Substance ID: DTXSID40447016
• Mol file: 125700-69-8.mol

Synonyms:TDBTU;125700-69-8;N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate;O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate;MFCD00077730;1,1,3,3-tetramethyl-2-(4-oxobenzo[d][1,2,3]triazin-3(4H)-yl)isouronium tetrafluoroborate;[dimethylamino-[(4-oxo-1,2,3-benzotriazin-3-yl)oxy]methylidene]-dimethylazanium;tetrafluoroborate;o-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-n,n,n',n'-tetramethyluroniumtetrafluoroborate;O-(4-Oxo-1,2,3-benzotriazin-3(4H)-yl)-N,N,N',N',-tetramethyluronium tetrafluoroborate;D04FKX;N,N,N,N-Tetramethyl-O-(3,4-Dihydro-4-Oxo-1,2,3-Benzotriazin-3-yl)Uronium Tetrafluoroborate;SCHEMBL528859;DTXSID40447016;FOBCPCIJLQTYBT-UHFFFAOYSA-N;AKOS015910161;AKOS025289340;CS-W009813;AS-17290;N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl) Uroniumtetrafluoroborate;D3263;FT-0654427;C93413;A805416;J-005268;J-523209;N,N,N',N'-Tetramethyl-o-(3,4-dhydro-4-oxo-1,2,3-benzotrazn-3-yl)uronum tetrafluoroborate;Methanaminium, N-[(dimethylamino)[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)oxy]methylene]-N-methyl-, tetrafluoroborate(1-) (1:1);N,N,N',N'-Tetramethyl-O-(4-oxo-3,4-dihydro-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate;O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyl uronium tetrafluoroborate;O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, >=95.0% (HPLC);TDBTUN,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)Uroniumtetrafluoroborate

Chemical Property of Tdbtu

Chemical Property:

• Melting Point: 147 °C (dec.)
• PSA: 63.26000
• LogP: 0.70980
• Storage Temp.: 2-8°C
• Sensitive.: Moisture & Light Sensitive
• Solubility.: acetonitrile: 0.1 g/mL, clear
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 3
• Exact Mass: 349.1333176
• Heavy Atom Count: 24
• Complexity: 420

Purity/Quality:

99% ^*data from raw suppliers

TDBTU ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 37-36/37/38
• Safety Statements: 22-24/25-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [B-](F)(F)(F)F.CN(C)C(=[N+](C)C)ON1C(=O)C2=CC=CC=C2N=N1
• Uses: O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate (2-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate, TBTU) may be used as coupling reagent in the synthesis of macrocyclic polyamine derivatives with various length of linkers, condensation reagent in the large-scale preparation of the hematoregulatory nonapeptide (Glp-Glu-Asp)2-DAS-(Lys)2 (2,SK&F 107647), coupling reagent for peptide synthesis which best suppresses racemization during fragment condensation.