4'-METHYL-2,2':6',2''-TERPYRIDINE

Base Information

• Chemical Name: 4'-METHYL-2,2':6',2''-TERPYRIDINE
• CAS No.: 72036-41-0
• Molecular Formula: C16H13N3
• Molecular Weight: 247.299
• Mol file: 72036-41-0.mol

Synonyms:4'-Methyl-2,2':6',2''-terpyridine;

Chemical Property of 4'-METHYL-2,2':6',2''-TERPYRIDINE

Chemical Property:

• Boiling Point: 401.464 °C at 760 mmHg
• Flash Point: 178.511 °C
• PSA: 38.67000
• Density: 1.145 g/cm³
• LogP: 3.51400

Purity/Quality:

99% ^*data from raw suppliers

4'-Methyl-2,2':6',2''-terpyridine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4'-METHYL-2,2':6',2''-TERPYRIDINE

There total 16 articles about 4'-METHYL-2,2':6',2''-TERPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

tetramethylstannane (594-27-4) + 4'-{[(Trifluoromethyl)sulfonyl]oxy}-2,2':6',2''-terpyridine (134653-69-3) → 4'-methyl-2,2':6',2''-terpyridine (72036-41-0)

Guidance literature:

With lithium chloride; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 130 ℃;

DOI:10.1016/S0040-4039(00)61466-1

Reference yield: 80.0%

methylmagnesium bromide (75-16-1) + 2,6-bis(2-pyridinyl)-4-(methylthio)pyridine (78570-35-1) → 4'-methyl-2,2':6',2''-terpyridine (72036-41-0)

Guidance literature:

With bis(triphenylphosphine)nickel(II) chloride; In diethyl ether; 1.) rt, 15 min 2.) reflux, 48 h;

DOI:10.1021/ja00247a021

Reference yield: 76.0%

3-Methyl-1,5-di-pyridin-2-yl-pentane-1,5-dione (207804-48-6) → 4'-methyl-2,2':6',2''-terpyridine (72036-41-0)

Guidance literature:

With ammonium acetate; In acetic acid; for 2h; Heating;

DOI:10.1002/(sici)1521-3765(19980416)4:4<723::aid-chem723>3.0.co;2-k

upstream raw materials:

2-Cyanopyridine

Li₂(TMM)(TMEDA)2

methyl magnesium iodide

2,6-bis(2-pyridinyl)-4-(methylthio)pyridine

Downstream raw materials:

4′-formyl-2,2′:6′2″-terpyridine

4'-(2'''-Phenylethyl)-2,2':6',2''-terpyridine

4'-Hentriacontyl-2,2':6',2''-terpyridine

4'-[(Diphenylphosphanyl)-methyl]-[2,2';6',2'']terpyridine

Refernces

• 1、 Fallahpour. "An efficient and easy route to trimethyl derivatives of 2,2':6',2''-terpyridine". . p. 1665 - 1667. Retrieved 2007/10/03.
• 2、 Holbrey, John D.,Tiddy, Gordon J. T.,Bruce, Duncan W.. "Amphiphilic Terpyridine Complexes of Ruthenium and Rhodium displaying Lyotropic Mesomorphism". . p. 1769 - 1774. Retrieved 2007/10/02.