N,N'-dibenzyl-2,3-diaminobutane

Base Information

• Chemical Name: N,N'-dibenzyl-2,3-diaminobutane
• CAS No.: 75825-39-7
• Molecular Formula: C₁₈H₂₄N₂
• Molecular Weight: 268.402
• Mol file: 75825-39-7.mol

Synonyms:N,N'-dibenzyl-2,3-diaminobutane

Chemical Property of N,N'-dibenzyl-2,3-diaminobutane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-dibenzyl-2,3-diaminobutane

There total 6 articles about N,N'-dibenzyl-2,3-diaminobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

dimethylglyoxal (431-03-8) + benzylamine (100-46-9) → N,N'-dibenzyl-2,3-diaminobutane (75825-39-7)

Guidance literature:

With hydrogen; platinum(IV) oxide; In methanol; at 60 ℃; for 10h; under 53200 Torr;

Reference yield: 20.0%

N-ethylidenebenzylamine (34233-75-5) → N-ethylbenzylamine (14321-27-8) + (2R,3S)-N,N'-Dibenzyl-butane-2,3-diamine (118824-81-0) + racemic bis-2,3-N,N'-dibenzyl diaminobutane (75825-39-7,118792-84-0,118824-81-0)

Guidance literature:

With titanium tetrachloride; magnesium; mercury dichloride; In tetrahydrofuran; at 0 ℃; for 12h; Yields of byproduct given;

DOI:10.1055/s-1988-27536

Reference yield:

N-ethylidenebenzylamine (34233-75-5) → N,N'-dibenzyl-2,3-diaminobutane (75825-39-7)

Guidance literature:

With potassium hydroxide; aluminium; In methanol; for 0.166667h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/00404-0399(50)1331-B

upstream raw materials:

dimethylglyoxal

benzylamine

N-ethylidenebenzylamine

meso-butane-2,3-diyl dimethanesulfonate

Downstream raw materials:

(4R,5R)-1,3-Dibenzyl-2,4,5-trimethyl-[1,3,2]diazaphospholidine 2-oxide

(4R,5R)-1,3-Dibenzyl-4,5-dimethyl-[1,3,2]diazaphospholidine 2-oxide

N,N'-dibenzyl-5,6-dimethyloctahydro-1,4,7-oxadiazonine

(4R,5R)-1,3-Dibenzyl-2-chloro-4,5-dimethyl-[1,3,2]diazaphospholidine

Refernces

• 1、 Baruah, Bipul. "Novel reductive coupling of aldimines to vicinal diamines". . p. 6747 - 6750. Retrieved 2007/10/02.
• 2、 Glinka, Ryszard,Mikiciuk-Olasik, Elzbieta,Kotelko, Barbara,Strzelczyk, Marek. "REACTIONS OF ALIPHATIC 1,2-DIAMINES WITH 2,2'-DICHLORODIETHYL ETHER". . p. 203 - 212. Retrieved 2007/10/02.