6-Methoxytrytophol

Base Information

• Chemical Name: 6-Methoxytrytophol
• CAS No.: 41340-31-2
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Hs Code.: 2933990090
• Mol file: 41340-31-2.mol

Synonyms:6-Methoxytrytophol;

Chemical Property of 6-Methoxytrytophol

Chemical Property:

• Melting Point: 96-97℃
• PSA: 45.25000
• Density: 1.124
• LogP: 1.71130

Purity/Quality:

99% ^*data from raw suppliers

1H-INDOLE-3-ETHANOL,6-METHOXY 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-Methoxytrytophol

There total 4 articles about 6-Methoxytrytophol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-(2-Ethoxycarbonyl-1-oxoethyl)-6-methoxy indole (68104-23-4) → 2-(6-methoxy-1H-indol-3-yl)ethan-1-ol (41340-31-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Heating;

DOI:10.1055/s-1986-31759

Reference yield:

(6-methoxy-1H-indol-3-yl)(oxo)acetyl chloride (68104-22-3) → 2-(6-methoxy-1H-indol-3-yl)ethan-1-ol (41340-31-2)

Guidance literature:

With tetrahydrofuran; lithium aluminium tetrahydride;

DOI:10.1021/jo01101a003

Reference yield:

6-methoxy-1-methyl-α-oxo-1H-indole-3-acetic acid methyl ester (408354-40-5) → 2-(6-methoxy-1H-indol-3-yl)ethan-1-ol (41340-31-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1039/c3cc47921h

upstream raw materials:

(6-methoxy-1H-indol-3-yl)(oxo)acetyl chloride

3-(2-Ethoxycarbonyl-1-oxoethyl)-6-methoxy indole

6-methoxy-1-methyl-α-oxo-1H-indole-3-acetic acid methyl ester

Downstream raw materials:

(3aR,8aS)-8-benzyl-6-methoxy-3,3a,8,8a-tetrahydro-2H-furo[2,3-b]indol-3a-ol

C₁₇H₂₇NO₂Si

C₂₄H₃₃NO₂Si

trigonoliimine B

Refernces

• 1、 -. "5-Sulphanyl-4h-1,2,4-triazole derivatives and their use as medicine". Page/Page column 22. . Retrieved 2008/06/13.
• 2、 Wender, P. A.,Schaus, J. M.,White, A. W.. "General Methodology for cis-Hydroisoquinoline Synthesis: Synthesis of Reserpine". . p. 6157 - 6159. Retrieved 2007/10/02.