rac-6-tert-butylcyclohex-2-enone

Base Information

• Chemical Name: rac-6-tert-butylcyclohex-2-enone
• CAS No.: 38510-79-1
• Molecular Formula: C₁₀H₁₆O
• Molecular Weight: 152.236
• Mol file: 38510-79-1.mol

Synonyms:rac-6-tert-butylcyclohex-2-enone

Chemical Property of rac-6-tert-butylcyclohex-2-enone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-6-tert-butylcyclohex-2-enone

There total 13 articles about rac-6-tert-butylcyclohex-2-enone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

6-(tert-butyl)cyclohex-2-en-1-ol → rac-6-tert-butylcyclohex-2-enone (38510-79-1)

Guidance literature:

With sodium hydrogencarbonate; Dess-Martin periodane; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.1c02173

Reference yield: 60.0%

anti-7-tert-butyl-3-diazobicyclo<2.2.1>heptan-2-one → rac-6-tert-butylcyclohex-2-enone (38510-79-1) + anti-5-tert-butyltricyclo<2.2.1.02.6>heptan-3-one (92974-05-5,93059-54-2) + 2-tert-Butyl-cyclohex-3-enecarboxylic acid (31752-75-7,31752-76-8) + (1R,3S,4S)-7-tert-Butyl-3-hydroxy-bicyclo[2.2.1]heptan-2-one (87405-49-0)

Guidance literature:

With hydrogenchloride; Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(00)81942-5

Reference yield:

2-tert-butylanisole (2944-48-1) → 2-tert-butylcyclohexanone (1728-46-7) + rac-6-tert-butylcyclohex-2-enone (38510-79-1)

Guidance literature:

With lithium; tert-butyl alcohol; in fluessigem NH₃ und anschl. mit wss. HCl;

DOI:10.1021/ja01599a024

upstream raw materials:

2-tert-butylanisole

2-(1,1-dimethylethyl)-benzenamine

tert-butylethylene

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Downstream raw materials:

1-(4-tert-butyl-3-oxo-cyclohexyl)-1-methyl-piperidinium; iodide

2-tert-butyl-5-piperidino-cyclohexanone

Refernces

• 1、 Yates, Peter,Kronis, John D.. "THE ACID INDUCED DECOMPOSITION OF 7-SUBSTITUTED 3-DIAZO-2-NORBORNANONES.THE STRUCTURES OF THE PRODUCTS AND THEIR DISTRIBUTION". . p. 2419 - 2422. Retrieved 2007/10/02.