Technology Process of 3-methoxy-4-iodopyrazole
There total 1 articles about 3-methoxy-4-iodopyrazole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-iodo-succinimide;
In
N,N-dimethyl-formamide;
at -30 ℃;
for 1.5h;
- Guidance literature:
-
2-5-dibromopyrazine; 3-methoxy-4-iodopyrazole;
With
t-BuBrettPhos; potassium tert-butylate; palladium diacetate;
In
toluene;
at 110 ℃;
for 24h;
Inert atmosphere;
Schlenk technique;
benzene-1,3-dicarboxylic-5-boronic triacid;
With
sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐4‐sulfonate; palladium diacetate; potassium carbonate;
In
water; toluene;
at 100 ℃;
for 48h;
Inert atmosphere;
Schlenk technique;
- Guidance literature:
-
3-methoxy-4-iodopyrazole; 3,6-diiodo-1,2,4,5-tetrazine;
With
t-BuBrettPhos; potassium tert-butylate; palladium diacetate;
In
toluene;
at 110 ℃;
for 20h;
Inert atmosphere;
Schlenk technique;
3-Carboxyphenylboronic acid;
With
sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐4‐sulfonate; palladium diacetate; sodium carbonate;
In
water; toluene;
at 100 ℃;
for 24h;
Inert atmosphere;
Schlenk technique;
