N-[2-(4-trifluoromethyl-2-nitrothiophenyl)phenyl]-N,N'-diacetylhydrazine

Base Information

• Chemical Name: N-[2-(4-trifluoromethyl-2-nitrothiophenyl)phenyl]-N,N'-diacetylhydrazine
• CAS No.: 1615684-30-4
• Molecular Formula: C₁₇H₁₄F₃N₃O₄S
• Molecular Weight: 413.377
• Mol file: 1615684-30-4.mol

Synonyms:N-[2-(4-trifluoromethyl-2-nitrothiophenyl)phenyl]-N,N'-diacetylhydrazine

Chemical Property of N-[2-(4-trifluoromethyl-2-nitrothiophenyl)phenyl]-N,N'-diacetylhydrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-(4-trifluoromethyl-2-nitrothiophenyl)phenyl]-N,N'-diacetylhydrazine

There total 2 articles about N-[2-(4-trifluoromethyl-2-nitrothiophenyl)phenyl]-N,N'-diacetylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

2-[(4-trifluoromethyl-2-nitrophenyl)thio]phenylhydrazine (1615684-47-3) + acetyl chloride (75-36-5) → N-[2-(4-trifluoromethyl-2-nitrothiophenyl)phenyl]-N,N'-diacetylhydrazine (1615684-30-4)

Guidance literature:

With triethylamine; In toluene; for 3h; Cooling with ice; Reflux;

DOI:10.1016/j.ejmech.2014.04.075

Reference yield:

2-[(4-trifluoromethyl-2-nitrophenyl)thio]aniline (322-71-4) → N-[2-(4-trifluoromethyl-2-nitrothiophenyl)phenyl]-N,N'-diacetylhydrazine (1615684-30-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite; tin(II) chloride dihdyrate

2: triethylamine / toluene / 3 h / Cooling with ice; Reflux

With tin(II) chloride dihdyrate; triethylamine; sodium nitrite; In toluene;

DOI:10.1016/j.ejmech.2014.04.075

upstream raw materials:

2-[(4-trifluoromethyl-2-nitrophenyl)thio]phenylhydrazine

acetyl chloride

2-[(4-trifluoromethyl-2-nitrophenyl)thio]aniline

Refernces