1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one)

Base Information

• Chemical Name: 1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one)
• CAS No.: 1335040-82-8
• Molecular Formula: C₂₈H₃₂N₈O₂
• Molecular Weight: 512.614
• Mol file: 1335040-82-8.mol

Synonyms:1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one)

Chemical Property of 1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one)

There total 1 articles about 1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

N,N'-diformylpiperazine (4164-39-0) + 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one (83-07-8) → 1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one) (1335040-82-8)

Guidance literature:

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one; With hydrogenchloride; In water; acetonitrile; for 0.25h; Heating;

N,N'-diformylpiperazine; In water; acetonitrile; at 20 - 85 ℃;

DOI:10.1080/15533174.2011.591322

Reference yield:

1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one) (1335040-82-8) + copper dichloride → [Cu(1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one)Cl2]

Guidance literature:

In acetonitrile; to a hot soln. of piperazine-compound in CH3CN a hot soln. of metal saltin CH3CN was added slowly with constant stirring, the mixt. was refluxe d for 8-10 h at 80-90°C; kept overnight at 0°C, ppt. was filtered off, washed with acetonitrile and dried under vac. over anhyd. P4O10; elem. anal.;

DOI:10.1016/j.saa.2011.06.032

Reference yield:

chromium(III) nitrate + 1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one) (1335040-82-8) → (Cr(1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one)(NO3)2))(NO3)

Guidance literature:

In acetonitrile; piperazine-compd. dissolved in CH3CN, heated for 10 min, hot Cr-compd. in CH3CN added slowly dropwise with constant stirring, refluxed for 8-10 h at 80-90°C, stored at room temp. for 2 h, cooled overnight at 0°C; filtered, washed with cold CH3CN, dried in vac. over P4O10, elem. anal.;

DOI:10.1080/15533174.2011.591322

upstream raw materials:

N,N'-diformylpiperazine

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one

Refernces

• 1、 Sharma, Amit Kumar,Chandra, Sulekh. "Spectroscopic and mycological studies of Co(II), Ni(II) and Cu(II) complexes with 4-aminoantipyrine derivative". . p. 424 - 430. Retrieved 2011.