1-(2-Isopropylthiazol-4-yl)-N-methylmethanamine hydrochloride

Base Information

• Chemical Name: 1-(2-Isopropylthiazol-4-yl)-N-methylmethanamine hydrochloride
• CAS No.: 908591-25-3
• Molecular Formula: C8H14 N2 S . Cl H
• Molecular Weight: 206.739
• Hs Code.: 2934100090
• DSSTox Substance ID: DTXSID70469589
• Mol file: 908591-25-3.mol

Synonyms:908591-25-3;1-(2-Isopropylthiazol-4-yl)-N-methylmethanamine hydrochloride;2-Isopropyl-4-[(N-methylamino)methyl]thiazole hydrochloride;2-Isopropyl-4(((N-methyl)amino)methyl)thiazole hydrochloride;N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amine, Hydrochloride Salt;N-methyl-1-(2-propan-2-yl-1,3-thiazol-4-yl)methanamine;hydrochloride;1-(2-ISOPROPYLTHIAZOL-4-YL)-N-METHYLMETHANAMINE HCL;C8H15ClN2S;SCHEMBL6090064;DTXSID70469589;MFCD07369525;N-methyl-1-(2-propan-2-yl-1,3-thiazol-4-yl)methanamine Hydrochloride;AKOS015915056;AC-8766;DS-18351;CS-0188468;FT-0652554;A843659;2-isopropyl-4-[((n-methylamino)methyl)thiazole hcl;2-Isopropyl-4-[(N-methylamino)methyl]thiazolehydrochloride;1-(2-Isopropylthiazol-4-yl)-N-methylmethanaminehydrochloride;N-methyl-1-(2-propan-2-yl-4-thiazolyl)methanamine hydrochloride;N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amine Hydrochloride;2-Isopropyl-4-[(N-methylamino)methyl]thiazole hydrochloride, AldrichCPR;N-Methyl-1-[2-(propan-2-yl)-1,3-thiazol-4-yl]methanamine--hydrogen chloride (1/1)

Chemical Property of 1-(2-Isopropylthiazol-4-yl)-N-methylmethanamine hydrochloride

Chemical Property:

• Vapor Pressure: 0.0643mmHg at 25°C
• Melting Point: 62-65°C
• Boiling Point: 230.9°C at 760 mmHg
• Flash Point: 93.4°C
• PSA: 53.16000
• LogP: 3.17880
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 206.0644474
• Heavy Atom Count: 12
• Complexity: 117

Purity/Quality:

99% ^*data from raw suppliers

N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amine,HydrochlorideSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C1=NC(=CS1)CNC.Cl
• Uses: Intermediate for Ritonavir, a kind of anti-AIDS pharmaceutical

Technology Process of 1-(2-Isopropylthiazol-4-yl)-N-methylmethanamine hydrochloride

There total 1 articles about 1-(2-Isopropylthiazol-4-yl)-N-methylmethanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-methyl-N-<(2-isopropyl-4-thiazolyl)methyl>amine (154212-60-9) → 2-isopropyl-4-(((N-methyl)amino)methyl)thiazole hydrochloride (908591-25-3)

Guidance literature:

With hydrogenchloride; In water; isopropyl alcohol; at 60 ℃; for 1h;

Reference yield:

2-isopropyl-4-(((N-methyl)amino)methyl)thiazole hydrochloride (908591-25-3) + N-<<(4-nitrophenyl)oxy>carbonyl>-L-valine methyl ester (162537-10-2) → N-((N-methyl-N-((2-isopropyl-4-thiazolyl)methyl)amino)carbonyl)-L-valine methyl ester (154248-99-4)

Guidance literature:

With dmap; triethylamine; In tetrahydrofuran; at 70 ℃; for 8h;

upstream raw materials:

N-methyl-N-<(2-isopropyl-4-thiazolyl)methyl>amine

Downstream raw materials:

N-((N-methyl-N-((2-isopropyl-4-thiazolyl)methyl)amino)carbonyl)-L-valine methyl ester

Refernces