3-OCTEN-2-ONE

Base Information

• Chemical Name: 3-OCTEN-2-ONE
• CAS No.: 18402-82-9
• Molecular Formula: C8H14O
• Molecular Weight: 126.199
• Mol file: 18402-82-9.mol

Synonyms:3-Octen-2-one,(E)- (8CI);(3E)-3-Octen-2-one;(E)-3-Octen-2-one;E-3-Octen-2-one;E-Oct-3-ene-2-one;trans-3-Octen-2-one;

Chemical Property of 3-OCTEN-2-ONE

Chemical Property:

• Vapor Pressure: 0.897mmHg at 25°C
• Refractive Index: n20/D 1.448(lit.)
• Boiling Point: 180.4 °C at 760 mmHg
• Flash Point: 67.1 °C
• PSA: 17.07000
• Density: 0.833 g/cm³
• LogP: 2.32180

Purity/Quality:

98%,99%, ^*data from raw suppliers

trans-3-Octen-2-one analytical standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10:
• Hazard Codes: R10:
• Statements: 10
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-OCTEN-2-ONE

There total 40 articles about 3-OCTEN-2-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(E)-oct-3-en-2-ol (57648-55-2) → (3E)-oct-3-en-2-one (18402-82-9)

Guidance literature:

With aluminum oxyhydroxide; ruthenium; In toluene; at 110 ℃; for 10h;

DOI:10.1021/ol060750z

Reference yield: 92.0%

1-hexene (592-41-6,25067-06-5) + methyl vinyl ketone (78-94-4,25038-87-3) → (3E)-oct-3-en-2-one (18402-82-9)

Guidance literature:

With copper(l) iodide; C₃₉H₅₂Cl₂N₂O₃Ru; In diethyl ether; at 35 ℃; for 16h; Concentration; Reagent/catalyst; Inert atmosphere;

DOI:10.1055/s-0033-1338425

Reference yield: 82.0%

[1-(2-Oxo-propyl)-pentyl]-triphenyl-phosphonium; perchlorate (85067-03-4) → (3E)-oct-3-en-2-one (18402-82-9)

Guidance literature:

With triethylamine; In methanol; chloroform; Ambient temperature;

DOI:10.1021/jo00157a028

upstream raw materials:

(E)-4-chloro-3-buten-2-one

di-n-butylcadmium

(E)-oct-3-en-2-ol

1-iodo-butane

Downstream raw materials:

(E)-4-methyl-N-(2-oxooct-3-en-1-yl)-N-tosylbenzenesulfonamide

Refernces

• 1、 Larock,R.C.,Bernhardt,J.C.. "-". . p. 710 - 719. Retrieved 1978.
• 2、 Clinet,J.C.,Linstrumelle,G.. "-". . p. 1137 - 1140. Retrieved 1978.
• 3、 Lee, Jeonghyo,Wang, Sibin,Callahan, Miranda,Nagorny, Pavel. "Copper(II)-Catalyzed Tandem Decarboxylative Michael/Aldol Reactions Leading to the Formation of Functionalized Cyclohexenones". supporting information. p. 2067 - 2070. Retrieved 2018/04/16.