(R)-1,2,3,4-tetrahydronaphthalen-1-amine

Base Information Edit

Chemical Name:(R)-1,2,3,4-tetrahydronaphthalen-1-amine
CAS No.:23357-46-2
Molecular Formula:C10H13N
Molecular Weight:147.22
Hs Code.:2921450090
European Community (EC) Number:628-771-4
UNII:F59J0838WR
DSSTox Substance ID:DTXSID201335739
Nikkaji Number:J835.611D
Wikidata:Q27452566
ChEMBL ID:CHEMBL289966
Mol file:23357-46-2.mol

Synonyms:23357-46-2;(R)-1,2,3,4-tetrahydronaphthalen-1-amine;(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine;(1R)-1,2,3,4-tetrahydronaphthalen-1-amine;(R)-1-Amino-1,2,3,4-tetrahydronaphthalene;(R)-1,2,3,4-Tetrahydro-1-naphthylamine;(R)-1-aminotetralin;(r)-1-aminotetraline;1-Naphthalenamine, 1,2,3,4-tetrahydro-, (1R)-;1-Aminotetralin, (R)-;CHEMBL289966;F59J0838WR;EC 628-771-4;MFCD00671629;1Y5;1,2,3,4-Tetrahydro-naphthalen-1-ylamine;Tetralin-1alpha-amine;SCHEMBL469047;UNII-F59J0838WR;(-)-1-AMINOTETRALIN;(r)-tetrahydro-1-naphthylamine;1-AMINOTETRALIN, (-)-;JRZGPXSSNPTNMA-SNVBAGLBSA-N;DTXSID201335739;BCP26610;CS-CU-00005;BDBM50023869;AKOS016843525;AM62763;CS-W007717;(R)-1,2,3,4-tetrahydronaphthaleneamine;AC-26800;CS-12282;(R)-1,2,3,4-tetrahydro-1-naphtylamine;(R)-1,2,3,4-Tetrahydro-1-napthylamine;(R)-1,2,3,4-tetrahydro-l-naphthylamine;(-)-1,2,3,4-Tetrahydro-1-naphthylamine;(1r)-1,2,3,4-tetrahydro-1-naphthylamine;A4907;T2926;(1R)-1,2,3,4-Tetrahydro-1-naphthalenamine;(R)-1,2,3,4-tetrahydronaphthalen-1-ylamine;(1R)-1,2,3,4-tetrahydronaphthalene-1-amine;(R)-1,2,3,4-tetrahydro-naphthalen-1-ylamine;EN300-344801;F13060;R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine;(1R)-1,2,3,4-tetrahydro-naphthalen-1-ylamine;(R)-(-)- 1,2,3,4-Tetrahydro-1-naphthylamine;(R)-(-)-1-Amino-1,2,3,4-tetrahydronaphthalene;(r)-(1,2,3,4-tetrahydro-naphthalen-1-yl)amine;J-015081;1-naphthalenamine, 1,2,3,4-tetrahydro-, (1r)- =;Q27452566;(1R)-1,2,3,4-TETRAHYDRO-.ALPHA.-NAPHTHYLAMINE;(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine, 97%;F8886-0005;(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine, ChiPros(R), produced by BASF, >=98.5% (GC)

Suppliers and Price of (R)-1,2,3,4-tetrahydronaphthalen-1-amine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine
10mg
$ 45.00

TCI Chemical
(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine
25G
$ 323.00

TCI Chemical
(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine
5G
$ 97.00

Sigma-Aldrich
(R)-(?)-1,2,3,4-Tetrahydro-1-naphthylamine ChiPros , produced by BASF, ≥98.5% (GC)
100g
$ 1000.00

Sigma-Aldrich
(R)-(?)-1,2,3,4-Tetrahydro-1-naphthylamine 97%
5g
$ 95.10

Sigma-Aldrich
(R)-(?)-1,2,3,4-Tetrahydro-1-naphthylamine 97%
25g
$ 317.00

Sigma-Aldrich
(R)-(?)-1,2,3,4-Tetrahydro-1-naphthylamine ChiPros , produced by BASF, ≥98.5% (GC)
25g
$ 306.00

Crysdot
(R)-1,2,3,4-Tetrahydronaphthalen-1-amine 98%
25g
$ 149.00

Chemenu
(R)-1-Amino-1,2,3,4-Tetrahydronaphthalene 95+%
25g
$ 131.00

Biosynth Carbosynth
(R)-1-Amino-1,2,3,4-tetrahydronaphthalene
5 g
$ 99.80

Total 91 raw suppliers

Chemical Property of (R)-1,2,3,4-tetrahydronaphthalen-1-amine Edit

Chemical Property:

Melting Point:116-119 °C
Refractive Index:1.565
Boiling Point:249.6 °C at 760 mmHg
PKA:9.39±0.20(Predicted)
Flash Point:110.8 °C
PSA：26.02000
Density:1.023 g/cm³
LogP:2.72300
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Sensitive.:Air Sensitive
Water Solubility.:Soluble in water (6.91g/L at 25°C).
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:147.104799419
Heavy Atom Count:11
Complexity:133

Purity/Quality:

99.9% ^*data from raw suppliers

(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, N
Hazard Codes:Xi,N,C
Statements: 36/37-51/53-36/37/38-52/53-34-22
Safety Statements: 26-36/37/39-61-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C2=CC=CC=C2C1)N
Isomeric SMILES:C1C[C@H](C2=CC=CC=C2C1)N
Uses (R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field. Chiral amines play an important role in stereoselective organic synthesis. They are used directly as resolving agents, building blocks or chiral auxiliaries.

Technology Process of (R)-1,2,3,4-tetrahydronaphthalen-1-amine

There total 28 articles about (R)-1,2,3,4-tetrahydronaphthalen-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 104354-39-4,192461-77-1
3,4-dihydro-naphthalen-1(2H)-one oxime O-methyl ether

: 23357-52-0
(S)-1,2,3,4-tetrahydronapht-1-yl-amine

: 23357-46-2
(R)-1,2,3,4-Tetrahydro-1-naphthylamine

Guidance literature:: With sodium tetrahydroborate; (S)-valinol; zirconium(IV) chloride; In tetrahydrofuran; Title compound not separated from byproducts; Ambient temperature;

Reference yield: 85.0%

: 119-64-2
tetralin

: 23357-46-2
(R)-1,2,3,4-Tetrahydro-1-naphthylamine

Guidance literature:: With C₅H₁₁NO*CHF₃O₃S; In ethanol; water; at 10 ℃; for 12h; pH=7.4; Reagent/catalyst; Concentration; enantioselective reaction; Inert atmosphere; Sealed tube; Enzymatic reaction;
DOI:10.1021/jacs.0c03428

Reference yield: 80.0%

: 529-34-0
3,4-dihydronaphthalene-1(2H)-one

: 23357-46-2
(R)-1,2,3,4-Tetrahydro-1-naphthylamine

Guidance literature:: With Candida boidinii formate dehydrogenase; Geobacillus stearothermophilus ε‐deaminating L‐lysine dehydrogenase variant 22; nicotinamide adenine dinucleotide; In aq. buffer; at 50 ℃; for 48h; pH=8.5; Reagent/catalyst; Enzymatic reaction;
DOI:10.1002/chem.202003140