Thiazol-5-ylmethanamine hydrochloride

Base Information

• Chemical Name: Thiazol-5-ylmethanamine hydrochloride
• CAS No.: 131052-46-5
• Molecular Formula: C₄H₆N₂S*ClH
• Molecular Weight: 150.632
• Hs Code.: 2934100090
• European Community (EC) Number: 802-828-5
• DSSTox Substance ID: DTXSID90590809
• Mol file: 131052-46-5.mol

Synonyms:131052-46-5;THIAZOL-5-YLMETHANAMINE HYDROCHLORIDE;5-Aminomethylthiazole HCl;C-Thiazol-5-yl-methylamine hydrochloride;1,3-thiazol-5-ylmethanamine;hydrochloride;5-Aminomethylthiazole hydrochloride;MFCD06738808;THIAZOL-5-YL-METHYLAMINE, HCL;(1,3-thiazol-5-yl)methanamine hydrochloride;1228838-25-2;5-Thiazolemethanamine dihydrochloride;5-(Aminomethyl)thiazole Hydrochloride;1,3-thiazol-5-ylmethanamine,hydrochloride;5-Thiazolmethylamine HCl;C-THIAZOL-4-YL-METHYLAMINEHYDROCHLORIDE;Thiazol-5-ylmethanamine HCl;SCHEMBL70364;DTXSID90590809;WZJFBMHEYMPACF-UHFFFAOYSA-N;Thiazol-5-ylmethanaminexhydrochloride;Thiazol-5-ylmethanamine xhydrochloride;AKOS016004390;AM91850;CS-W005433;DS-2400;(Thiazol-5-yl)methanamine hydrochloride;C-thiazol-5-ylmethylamine, hydrochloride;SY025293;DB-062794;5-thiazolemethanamine hydrochloride, AldrichCPR;EN300-313579;A806189;J-524905;1-(1,3-THIAZOL-5-YL)METHANAMINE HYDROCHLORIDE;1-(1,3-Thiazol-5-yl)methanamine--hydrogen chloride (1/1)

Chemical Property of Thiazol-5-ylmethanamine hydrochloride

Chemical Property:

• Boiling Point: 255.1 °C at 760 mmHg
• Flash Point: 108.1 °C
• PSA: 67.15000
• LogP: 2.10410
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 150.0018471
• Heavy Atom Count: 8
• Complexity: 57.7

Purity/Quality:

99% ^*data from raw suppliers

Thiazol-5-ylmethanaminehydrochloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(SC=N1)CN.Cl

Technology Process of Thiazol-5-ylmethanamine hydrochloride

There total 2 articles about Thiazol-5-ylmethanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

5-(azidomethyl)thiazole → 5-(aminomethyl)thiazole hydrochloride (131052-46-5,1215372-00-1)

Guidance literature:

5-(azidomethyl)thiazole; With triphenylphosphine; at 110 ℃; for 20h; Green chemistry;

With hydrogenchloride; In 1,4-dioxane; diethyl ether; Green chemistry;

DOI:10.1039/c8gc02136h

Reference yield:

→ 5-(aminomethyl)thiazole hydrochloride (131052-46-5,1215372-00-1) + 5-(aminomethyl)thiazole (161805-76-1)

Guidance literature:

Refernces

• 1、 Lenstra, Danny C.,Lenting, Peter E.,Mecinovi?, Jasmin. "Sustainable organophosphorus-catalysed Staudinger reduction". supporting information. p. 4418 - 4422. Retrieved 2018/10/17.