CHLOROACETYL CHLORIDE, [1-14C]

Base Information

• Chemical Name: CHLOROACETYL CHLORIDE, [1-14C]
• CAS No.: 74094-67-0
• Molecular Formula: C2H2 Cl2 O
• Molecular Weight: 114.96
• Mol file: 74094-67-0.mol

Synonyms:Acetyl-1-14Cchloride, chloro- (6CI); Chloroacetyl chloride-1-14C

Chemical Property of CHLOROACETYL CHLORIDE, [1-14C]

Chemical Property:

• PSA: 17.07000
• LogP: 0.99060

Purity/Quality:

99% ^*data from raw suppliers

CHLOROACETYLCHLORIDE[1-14C] 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHLOROACETYL CHLORIDE, [1-14C]

There total 3 articles about CHLOROACETYL CHLORIDE, [1-14C] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

<1-14C>Chloroacetic acid (1633-46-1) + Phthaloyl dichloride (88-95-9) → chloro[1‐14C]acetyl chloride (74094-67-0)

Guidance literature:

at 135 ℃; for 2h;

Reference yield:

<1-14C>Chloroacetic acid (1633-46-1) → chloro[1‐14C]acetyl chloride (74094-67-0)

Guidance literature:

With thionyl chloride; In benzene; for 2h; Heating;

DOI:10.3109/00498259409043297

Reference yield:

→ chloro[1‐14C]acetyl chloride (74094-67-0)

Guidance literature:

C6H5-COCl, Cl-CH2-¹⁴CO2H;

DOI:10.1002/jlcr.2580160609

upstream raw materials:

<1-14C>Chloroacetic acid

Phthaloyl dichloride

Refernces

• 1、 Zerjatke. "Synthesis of 3-carbethoxyamino-5-dimethylamino-[1-14C]- acetyl-10,11-dihydro-5H-dibenz[b,f]azepine-hydrochloride". . p. 874 - 874. Retrieved 2007/10/02.