Cyanamide, [14C]

Base Information

• Chemical Name: Cyanamide, [14C]
• CAS No.: 21420-36-0
• Molecular Formula: CH2 N2
• Molecular Weight: 44.0293
• DSSTox Substance ID: DTXSID301317679
• Mol file: 21420-36-0.mol

Synonyms:21420-36-0;CYANAMIDE, [14C];Cyanamide-14C;DTXSID301317679

Chemical Property of Cyanamide, [14C]

Chemical Property:

• PSA: 49.81000
• LogP: 0.12648
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 44.02504006
• Heavy Atom Count: 3
• Complexity: 29.3

Purity/Quality:

99% ^*data from raw suppliers

CYANAMIDE-[14C] 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(#N)N
• Isomeric SMILES: [14C](#N)N

Technology Process of Cyanamide, [14C]

There total 6 articles about Cyanamide, [14C] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

sodium azide + ammonia (7664-41-7) + barium [14-C]carbonate (1882-53-7,51118-03-7,58454-84-5) → [14C]cyanamide (21420-36-0)

Guidance literature:

heating for 1 h; cooling down in NH3-stream;

DOI:10.1021/ja01164a524

Reference yield: 75.3%

barium <14 C>cyanamide → [14C]cyanamide (21420-36-0)

Guidance literature:

With sulfuric acid; In water; at 0 - 5 ℃; for 1.25h;

DOI:10.1002/jlcr.1577

Reference yield: 73.5%

ammonia (7664-41-7) + barium [14-C]carbonate (1882-53-7,51118-03-7,58454-84-5) → [14C]cyanamide (21420-36-0)

Guidance literature:

With hydrogenchloride; sulfuric acid; In water; byproducts: BaSO4; dry NH3 reacted with Ba(14)CO3 at 850°C for 3 h; cooling down to room temp.; treated with ice-water for 30 min; adding of H2SO4 to soln. and stirring for 1 h; acidifying with HCl to pH=5.5; centrifugation of BaSO4; evapn. to dryness under 40°C and under reduced pressure; extraction with ether; drying over P2O5 in vac.;

DOI:10.1021/ja01174a091

upstream raw materials:

ammonia

barium [14-C]carbonate

(14C)Cyanogen bromide

Downstream raw materials:

N-(2-methyl-5-nitro-phenyl)[⁽¹⁴⁾C]quanidine

[¹⁴C]urea

4-(⁽¹⁴⁾C-guanidino)benzoic acid hydrochloride

<(14)C>thiourea

Refernces

• 1、 Murthy, Akula,Ullas, Giliyar. "Synthesis of [14C] labeled 2-methoxypyrimidine-5-carboxylic acid". . p. 114 - 116. Retrieved 2009.
• 2、 Murray,Ronzio. "-". . p. 2245. Retrieved 1949.
• 3、 Winnicka, Elzbieta,Kanska, Marianna. "Synthesis of2H-, and3H-labeled indole and L-tryptophan". scheme or table. p. 483 - 483. Retrieved 2011/05/04.