2-Mesitylmagnesium bromide

Base Information

• Chemical Name: 2-Mesitylmagnesium bromide
• CAS No.: 2633-66-1
• Molecular Formula: C9H11BrMg
• Molecular Weight: 223.395
• Hs Code.: 29319090
• European Community (EC) Number: 627-075-8
• Mol file: 2633-66-1.mol

Synonyms:2633-66-1;2-mesitylmagnesium bromide;mesitylmagnesium bromide;2,4,6-Trimethylphenylmagnesium bromide;MFCD00009663;Magnesium, bromo(2,4,6-trimethylphenyl)-;MesMgBr;2-Mesitymagnesium bromide;2,4,6-TRIMETHYLPHENYLMAGNESIUMBROMIDE;SCHEMBL366710;YXVSITSUDRGILL-UHFFFAOYSA-M;AKOS015912800;Magnesium,bromo(2,4,6-trimethylphenyl)-;magnesium;1, 3, 5-trimethylbenzene-6-ide;bromide;2,4,6-Trimethylphenylmagnesium bromide, 0.5 M in THF;2,4,6-Trimethylphenylmagnesium bromide, 1M in 2-MeTHF;2,4,6-Trimethylphenylmagnesium bromide, 1.0 M in 2-MeTHF;2,4,6-Trimethylphenylmagnesium bromide 0.5 M in Tetrahydrofuran

Chemical Property of 2-Mesitylmagnesium bromide

Chemical Property:

• Flash Point: 1 °F
• PSA: 0.00000
• Density: 1.005 g/mL at 25 °C
• LogP: 3.25760
• Sensitive.: Air & Moisture Sensitive
• Water Solubility.: It reacts with water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 221.98945
• Heavy Atom Count: 11
• Complexity: 190

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Mesitylmagnesium bromide solution 1.0 M in THF ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F+FC
• Hazard Codes: F+,C,F
• Statements: 12-14-19-20/21/22-34-11-67-22-40-37
• Safety Statements: 45-36/37/39-26-16

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=[C-]C(=C1)C)C.[Mg+2].[Br-]
• Uses: 2,4,6-Trimethylphenylmagnesium bromide is used as an organic chemical synthesis intermediate.

Technology Process of 2-Mesitylmagnesium bromide

There total 4 articles about 2-Mesitylmagnesium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-trimethylphenyl bromide (576-83-0) → 2-mesitylmagnesium bromide (2633-66-1)

Guidance literature:

With magnesium; In tetrahydrofuran; at 80 ℃; for 0.333333h; microwave irradiation;

DOI:10.1016/j.tet.2005.09.022

Reference yield:

2,4,6-trimethylphenyl bromide (576-83-0) → 2-mesitylmagnesium bromide (2633-66-1)

Guidance literature:

With copper-magnesium alloy; diethyl ether; iodine;

Reference yield:

1,2-bis(bis(3,5-di-tert-butylphenyl)phosphino)benzene (1203710-18-2) + Fe(mesityl)3- → Fe(mesityl)2(SciOPP) + 2-mesitylmagnesium bromide (2633-66-1)

Guidance literature:

In tetrahydrofuran; 2-methyltetrahydrofuran; Glovebox;

DOI:10.1021/ja503596m

upstream raw materials:

2,4,6-trimethylphenyl bromide

1,2-bis(bis(3,5-di-tert-butylphenyl)phosphino)benzene

Downstream raw materials:

2-(2,4,6-trimethylphenyl)ethanol

2'-hydroxymethyl-2,4,6-trimethyl-benzophenone

2-methyl-6-(2,4,6-trimethyl-benzoyl)-benzoic acid

3-methyl-2-(2,4,6-trimethyl-benzoyl)-benzoic acid

Refernces

• 1、 Thakuri, Rajendr S.,Schmidt, Joseph A. R.. "Palladium-Based Hydroamination Catalysts Employing Sterically Demanding 3-Iminophosphines: Branched Kinetic Products by Prevention of Allylamine Isomerization". . p. 1917 - 1927. Retrieved 2019/05/21.
• 2、 Daifuku, Stephanie L.,Al-Afyouni, Malik H.,Snyder, Benjamin E. R.,Kneebone, Jared L.,Neidig, Michael L.. "A combined m?ssbauer, magnetic circular dichroism, and density functional theory approach for iron cross-coupling catalysis: Electronic structure, in situ formation, and reactivity of iron-mesityl-bisphosphines". . p. 9132 - 9143. Retrieved 2014/07/08.