C₁₇H₁₆O₂

Base Information

• Chemical Name: C₁₇H₁₆O₂
• CAS No.: 20412-18-4
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.313
• Mol file: 20412-18-4.mol

Synonyms:C₁₇H₁₆O₂

Chemical Property of C₁₇H₁₆O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₆O₂

There total 19 articles about C₁₇H₁₆O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-Methoxystyrene (637-69-4,24936-44-5) + para-chloroacetophenone (99-91-2) → 1-[4-[(E)-2-(4-methoxyphenyl)vinyl]phenyl]ethanone (20412-18-4,117760-54-0)

Guidance literature:

With tetrabutylammomium bromide; sodium acetate; C₈₄H₆₀N₁₂O₈Pd₄; at 140 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.organomet.0c00791

Reference yield: 98.0%

4-Methoxystyrene (637-69-4,24936-44-5) + 4-Iodoacetophenone (13329-40-3) → C17H16O2 (20412-18-4)

Guidance literature:

With potassium hydroxide; In water; N,N-dimethyl-formamide; at 90 ℃; for 1h;

DOI:10.1080/00958972.2014.995100

Reference yield: 98.0%

→ C17H16O2 (20412-18-4)

Guidance literature:

With potassium hydroxide; In water; N,N-dimethyl-formamide; at 80 ℃; for 6h;

upstream raw materials:

4-Methoxystyrene

4-acetylphenyldiazonium chloride

para-bromoacetophenone

4-Iodoacetophenone

Refernces

• 1、 Hung, Cheng-Hau,Zheng, Wei-Yuan,Lee, Hon Man. "Palladium Complexes with Phenoxy- And Amidate-Functionalized N-Heterocyclic Carbene Ligands Based on 3-Phenylimidazo[1,5- a]pyridine: Synthesis and Catalytic Application in Mizoroki-Heck Coupling Reactions with Ortho-Substituted Aryl Chlorides". . p. 702 - 713. Retrieved 2021/04/02.
• 2、 Liu, Li-Cheng,Tzeng, Yan-Hsiang,Hung, Cheng-Hau,Lee, Hon Man. "Multidentate N-Heterocyclic Carbene Complexes of Nickel and Palladium: Structural Analysis and Catalytic Application in Mizoroki–Heck Coupling Reaction". . p. 3601 - 3611. Retrieved 2020/09/01.