4-(Tributylstannyl)pyridine

Base Information

• Chemical Name: 4-(Tributylstannyl)pyridine
• CAS No.: 124252-41-1
• Molecular Formula: C17H31NSn
• Molecular Weight: 368.15
• Hs Code.: 2933399090
• European Community (EC) Number: 677-925-7
• DSSTox Substance ID: DTXSID60371985
• Mol file: 124252-41-1.mol

Synonyms:4-(Tributylstannyl)pyridine;124252-41-1;tributyl(pyridin-4-yl)stannane;4-TRIBUTYLSTANNYLPYRIDINE;Pyridine, 4-(tributylstannyl)-;4-tributylstannyl-pyridine;MFCD01319071;4-(TRI-N-BUTYLSTANNYL)PYRIDINE;Pyridine,4-(tributylstannyl)-;4-(1,1,1-Tributylstannyl)pyridine;4-(Tri-n-butylstannyl)pyridine;4-(Tributylstannanyl)pyridine;4-Pyridyltributyltin;4-Tributyltinpyridine;Tributyl-4-pyridylstannane;(Pyridin-4-yl)tributylstannane;(4-pyridyl)tributyltin;4-tributyistannylpyridine;tributyl(4-pyridinyl)tin;4-pyridyl-tributylstannane;4-tributylstannanylpyridine;4-tributylstannanyl-pyridine;4-tri-n-butylstannylpyridine;4(tri-n-butylstannyl)pyridine;SCHEMBL658276;DTXSID60371985;UNEPXPMBVGDXGH-UHFFFAOYSA-N;AMY18346;ZEA25241;4-PYRIDYLTRI-N-BUTYLSTANNANE;4-tributylstannylpyridine, AldrichCPR;AKOS015843046;AB08884;PS-9700;SY034743;FT-0676563;A50077;EN300-225237;J-005059;J-513891

Chemical Property of 4-(Tributylstannyl)pyridine

Chemical Property:

• Vapor Pressure: 1.43E-05mmHg at 25°C
• Melting Point: 243-246 °C
• Boiling Point: 377.8 °C at 760 mmHg
• PKA: 6.45±0.10(Predicted)
• Flash Point: 182.3 °C
• PSA: 12.89000
• LogP: 5.13770
• Storage Temp.: Keep Cold
• Water Solubility.: Not miscible in water. Soluble in ether, hexane and tetrahydrofuran.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 10
• Exact Mass: 369.147853
• Heavy Atom Count: 19
• Complexity: 190

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(Tributylstannyl)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T, Xi
• Hazard Codes: T,Xi,N
• Statements: 21-25-36/38-48/23/25-50/53
• Safety Statements: 36/37/39-45-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC[Sn](CCCC)(CCCC)C1=CC=NC=C1
• Uses: 4-(Tri-n-butylstannyl)pyridine is used as organic chemical synthesis intermediate.

Technology Process of 4-(Tributylstannyl)pyridine

There total 4 articles about 4-(Tributylstannyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromopyridin (1120-87-2) + tributyltin chloride (1461-22-9) → (pyridin-4-yl)tributyltin (124252-41-1)

Guidance literature:

4-bromopyridin; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 2h; Schlenk technique; Inert atmosphere;

tributyltin chloride; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1002/adsc.201601289

Reference yield:

→ (pyridin-4-yl)tributyltin (124252-41-1)

Guidance literature:

Reference yield:

→ 1,4-Dihydro-1-(2-chloro-4-hydroxyphenyl)-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxamide (164261-17-0) + (pyridin-4-yl)tributyltin (124252-41-1)

Guidance literature:

upstream raw materials:

4-bromopyridin

tributyltin chloride

Downstream raw materials:

p-phenylpyridine

4-(2-nitrophenyl)-pyridine

4-(4-Methoxy-2-nitro-phenyl)-pyridine

9-benzyl-6-(4-pyridyl)purine

Refernces

• 1、 -. "Fused pyrazole derivatives bieng protein kinase inhibitors". . . Retrieved 2008/06/13.
• 2、 -. "HETERO-BIARYL-PYRIDOQUINAZOLINONE DERIVATIVES AS ANTI-CANCER AGENTS". . . Retrieved 2008/06/13.