Z-Phg-OH

Base Information Edit

Chemical Name:Z-Phg-OH
CAS No.:53990-33-3
Molecular Formula:C₁₆H₁₅NO₄
Molecular Weight:285.299
Hs Code.:29242990
DSSTox Substance ID:DTXSID20356056
Nikkaji Number:J72.296K
Wikidata:Q72441913
Mol file:53990-33-3.mol

Synonyms:Z-Phg-OH;53990-33-3;Z-L-phenylglycine;(S)-2-(BENZYLOXYCARBONYLAMINO)-2-PHENYLACETIC ACID;(S)-2-(((Benzyloxy)carbonyl)amino)-2-phenylacetic acid;(2S)-2-phenyl-2-(phenylmethoxycarbonylamino)acetic acid;MFCD00077033;Cbz-L-(+)-Phenylglycine;Cbz-Phg-OH;Z-L-2-phenylglycine;(2s)-{[(benzyloxy)carbonyl]amino}(phenyl)acetic acid;Z-L-PHG-OH;(2S)-2-[[(benzyloxy)carbonyl]amino]-2-phenylacetic acid;(2S)-2-{[(benzyloxy)carbonyl]amino}-2-phenylacetic acid;SCHEMBL434233;DTXSID20356056;N-Carbobenzoxy-L-2-phenylglycine;RLDJWBVOZVJJOS-AWEZNQCLSA-N;n-benzyloxycarbonyl-l-phenylglycine;AM1061;AKOS015839334;(s)-2-(cbz-amino)-2-phenylacetic acid;Z-Phg-OH, >=99.0% (HPLC);(S)-N-Cbz-2-amino-2-phenylacetic Acid;AS-17589;SY033674;C2567;CS-0015745;D70463;EN300-122144;(S)-BENZYLOXYCARBONYLAMINO-PHENYL-ACETIC ACID;J-300368;(2S)-2-{[(benzyloxy)carbonyl]amino}-2-phenylethanoic acid;N-alpha-BenZyloxycarbonyl-L-phenylglycine (CbZ-L-Phg-OH);Benzeneacetic acid, alpha-[[(phenylmethoxy)carbonyl]amino]-, (alphaS)-

Suppliers and Price of Z-Phg-OH

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Z-L-Phenylglycine
50g
$ 80.00

TRC
Z-L-Phenylglycine
25g
$ 60.00

TRC
Z-L-Phenylglycine
10g
$ 50.00

TRC
Z-L-Phenylglycine
5g
$ 45.00

TCI Chemical
N-Carbobenzoxy-L-2-phenylglycine >98.0%(HPLC)(T)
5g
$ 38.00

TCI Chemical
N-Carbobenzoxy-L-2-phenylglycine >98.0%(HPLC)(T)
1g
$ 15.00

Sigma-Aldrich
Z-Phg-OH ≥99.0% (HPLC)
5g-f
$ 153.00

Sigma-Aldrich
Z-Phg-OH ≥99.0% (HPLC)
5 g
$ 106.00

Iris Biotech GmbH
Z-L-Phg-OH
100 g
$ 540.00

Iris Biotech GmbH
Z-L-Phg-OH
25 g
$ 168.75

Total 99 raw suppliers

Chemical Property of Z-Phg-OH Edit

Chemical Property:

Vapor Pressure:1.25E-10mmHg at 25°C
Melting Point:131.0 to 135.0 °C
Refractive Index:1.599
Boiling Point:495.3 °C at 760 mmHg
PKA:3.49±0.10(Predicted)
Flash Point:253.4 °C
PSA：75.63000
Density:1.275 g/cm³
LogP:3.12960
Storage Temp.:Store at RT.
Solubility.:DMSO (Slightly), Ethanol (Slightly)
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:285.10010796
Heavy Atom Count:21
Complexity:346

Purity/Quality:

99% ^*data from raw suppliers

Z-L-Phenylglycine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NC(C2=CC=CC=C2)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)N[C@@H](C2=CC=CC=C2)C(=O)O
Uses Z-L-Phenylglycine is an intermediate for the synthesis of Asimadoline Hydrochlorine (A788250), used in the treatment of IBS, a disorder associated with pain and altered bowel function.

Technology Process of Z-Phg-OH

There total 21 articles about Z-Phg-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%