2,4-Dibromobenzenesulfonyl chloride

Base Information

• Chemical Name: 2,4-Dibromobenzenesulfonyl chloride
• CAS No.: 72256-95-2
• Molecular Formula: C6H3Br2ClO2S
• Molecular Weight: 334.416
• Hs Code.: 2904909090
• European Community (EC) Number: 620-773-3
• DSSTox Substance ID: DTXSID60372018
• Wikidata: Q82159596
• Mol file: 72256-95-2.mol

Synonyms:2,4-Dibromobenzenesulfonyl chloride;72256-95-2;2,4-dibromobenzene-1-sulfonyl chloride;2,4-dibromobenzenesulphonyl chloride;MFCD03093759;SCHEMBL1814581;DTXSID60372018;OMOXIKAWVFDFNX-UHFFFAOYSA-N;XCA25695;BBL100096;STL301717;2,4-DIBROMOphenylsulfonyl CHLORIDE;2,4-dibromobenzene-1-sulfonylchloride;AKOS000147314;PS-10909;2,4-Dibromobenzenesulfonyl chloride, 98%;FT-0641401;EN300-45018;A837468;J-507103

Chemical Property of 2,4-Dibromobenzenesulfonyl chloride

Chemical Property:

• Vapor Pressure: 0.00019mmHg at 25°C
• Melting Point: 82-86 °C(lit.)
• Refractive Index: 1.622
• Boiling Point: 338.6 °C at 760 mmHg
• Flash Point: 158.6 °C
• PSA: 42.52000
• Density: 2.11g/cm3
• LogP: 4.21990
• Storage Temp.: 2-8°C
• Sensitive.: Moisture Sensitive
• Water Solubility.: Insoluble in water.
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 333.78885
• Heavy Atom Count: 12
• Complexity: 249

Purity/Quality:

99% ^*data from raw suppliers

2,4-Dibromobenzenesulfonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Br)Br)S(=O)(=O)Cl
• Uses: 2,4-Dibromobenzenesulfonyl chloride is used as pharmaceutical intermediate.

Technology Process of 2,4-Dibromobenzenesulfonyl chloride

There total 3 articles about 2,4-Dibromobenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-dibromobenzene (108-36-1) → 2,4-dibromobenzene-1-sulfonyl chloride (72256-95-2)

Guidance literature:

With chlorosulphuric acid;

DOI:10.1021/ja01860a014

Reference yield:

→ 2,4-dibromobenzene-1-sulfonyl chloride (72256-95-2)

Guidance literature:

With phosphorus pentachloride;

Reference yield:

→ 2,4-dibromobenzene-1-sulfonyl chloride (72256-95-2)

Guidance literature:

DOI:10.1111/j.2042-7158.1960.tb12684.x

upstream raw materials:

1,3-dibromobenzene

Downstream raw materials:

N-(4-carbamimidoyl-phenyl)-N'-{1-[3-(5-chloro-thiophen-2-yl)-4-(morpholine-4-sulfonyl)-phenyl]-ethyl}-malonamide trifluoroacetate

Refernces

• 1、 BOGGIANO,CONDON,DAVIES,JACKMAN,OVERELL,PETROW,STEPHENSON,WILD. "Studies in the field of diuretic drugs. Part II. 5-Chloro-2,4-disulphamyltoluene (disulphamide).". . p. 419 - 425. Retrieved 2007/10/13.