1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonyl Fluoride

Base Information

• Chemical Name: 1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonyl Fluoride
• CAS No.: 104729-49-9
• Molecular Formula: C4HF9O3S
• Molecular Weight: 300.10
• Hs Code.: 2909199090
• DSSTox Substance ID: DTXSID40446988
• Nikkaji Number: J790.482G
• Wikidata: Q82265753
• Mol file: 104729-49-9.mol

Synonyms:104729-49-9;1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonyl Fluoride;1,1,2,2-Tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulphonyl fluoride;1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethane-1-sulfonyl fluoride;DTXSID40446988;MFCD07778617;AKOS015898897;5H-3-Oxa-octafluoropentanosulfonyl fluoride;FT-0717782;H11739;A801045;4-Difluoromethyl-perfluoro-3-oxabutanesulfonyl fluoride;4-N-OCTYLOXYBENZOICACID2,4,5-TRICHLOROPHENYLESTER;1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonylFluoride;1,1,2,2-Tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonic acid fluoride;1,1,2,2-tetrakis(fluoranyl)-2-[1,1,2,2-tetrakis(fluoranyl)ethoxy]ethanesulfonyl fluoride

Chemical Property of 1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonyl Fluoride

Chemical Property:

• Vapor Pressure: 11mmHg at 25°C
• Refractive Index: 1.301
• Boiling Point: 132.2 °C at 760 mmHg
• Flash Point: 33.8 °C
• PSA: 51.75000
• Density: 1.749 g/cm³
• LogP: 3.42660
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 5
• Exact Mass: 299.95026852
• Heavy Atom Count: 17
• Complexity: 368

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,1,2,2-Tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulphonylFluoride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(OC(C(F)(F)S(=O)(=O)F)(F)F)(F)F)(F)F
• Uses: 1,1,2,2-Tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulphonyl Fluoride is a useful reactant in organic synthesis.

Technology Process of 1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonyl Fluoride

There total 2 articles about 1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonyl Fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

polytetrafluoroethylene (116-14-3,82785-14-6) + tetrafluoroethane-β-sultone (697-18-7) → 5-hydro-3-oxaoctafluoropentanesulfonyl fluoride (104729-49-9)

Guidance literature:

With sulfuric acid; silver fluoride; In diethylene glycol dimethyl ether; at 20 ℃; for 565h; Solvent; Reagent/catalyst; Autoclave; Cooling with ice;

Reference yield: 52.0%

tetrafluoroethane-β-sultone (697-18-7) → 5-hydro-3-oxaoctafluoropentanesulfonyl fluoride (104729-49-9)

Guidance literature:

With sulfuric acid; silver fluoride; In 2,2,2-trifluoroethanol; diethylene glycol dimethyl ether; at 20 ℃; under 3000.3 Torr; Autoclave; Inert atmosphere; Cooling with acetone-dry ice;

Reference yield: 95.0%

19-hydroxytestosterone (2126-37-6) + 5-hydro-3-oxaoctafluoropentanesulfonyl fluoride (104729-49-9) → 5β,19-Cycloandrost-1-ene-3,17-dione (3133-52-6)

Guidance literature:

With triethylamine; In toluene; at 30 ℃;

DOI:10.1016/S0022-1139(99)00175-X

upstream raw materials:

polytetrafluoroethylene

tetrafluoroethane-β-sultone

Downstream raw materials:

p-Chlorotetrafluorophenyl 5H-3-oxaperfluoropentanesulfonate

1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)-ethanesulfonyl azide

1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)-ethanesulfonyl amide

3,17-Dioxo-6β,19-cyclo-androst-4-en

Refernces

• 1、 -. "METHOD FOR PRODUCING FLUORINE-CONTAINING ETHER". Paragraph 0056. . Retrieved 2017/05/06.