Oxazole-2-carboxylic acid hydrazide

Base Information

• Chemical Name: Oxazole-2-carboxylic acid hydrazide
• CAS No.: 90831-48-4
• Molecular Formula: C4H5 N3 O2
• Molecular Weight: 127.103
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID80459698
• Nikkaji Number: J1.865.003G
• Mol file: 90831-48-4.mol

Synonyms:90831-48-4;Oxazole-2-carboxylic acid hydrazide;OXAZOLE-2-CARBOHYDRAZIDE;1,3-oxazole-2-carbohydrazide;2-oxazolecarbohydrazide;2-OXAZOLECARBOXYLIC ACID, HYDRAZIDE;SCHEMBL4538623;2-Oxazolecarboxylicacid,hydrazide;Oxazole-2-carboxylicacidhydrazide;DTXSID80459698;MFCD04114927;AKOS006293915;AB19281;CS-0321890;FT-0695865;A843651

Chemical Property of Oxazole-2-carboxylic acid hydrazide

Chemical Property:

• PSA: 81.15000
• LogP: 0.36930
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 127.038176411
• Heavy Atom Count: 9
• Complexity: 116

Purity/Quality:

98%min ^*data from raw suppliers

Oxazole-2-carboxylicacidhydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=N1)C(=O)NN

Technology Process of Oxazole-2-carboxylic acid hydrazide

There total 2 articles about Oxazole-2-carboxylic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

→ oxazole-2-carbohydrazide (90831-48-4)

Guidance literature:

Reference yield:

ethyl oxazole-2-carboxylate (33036-67-8) → oxazole-2-carbohydrazide (90831-48-4)

Guidance literature:

With hydrazine hydrate;

Reference yield: 84.0%

oxazole-2-carbohydrazide (90831-48-4) + benzil (134-81-6) → 3-oxazol-2-yl-5,6-diphenyl-[1,2,4]triazine

Guidance literature:

With ammonium acetate; In acetic acid; at 180 ℃; for 0.0833333h; Further Variations:; Reaction partners; Product distribution; microwave irradiation;

DOI:10.1016/S0040-4039(02)02845-9

upstream raw materials:

ethyl oxazole-2-carboxylate

Refernces