(Pyridin-3-yloxy)-acetic acid

Base Information

• Chemical Name: (Pyridin-3-yloxy)-acetic acid
• CAS No.: 86649-57-2
• Molecular Formula: C7H7NO3
• Molecular Weight: 153.137
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID90390205
• Wikidata: Q72504734
• Mol file: 86649-57-2.mol

Synonyms:86649-57-2;(Pyridin-3-yloxy)-acetic acid;3-Pyridyloxyacetic acid;2-(Pyridin-3-yloxy)acetic acid;2-pyridin-3-yloxyacetic acid;2-(3-pyridyloxy)acetic acid;MFCD04039772;(pyridin-3-yloxy)acetic acid;(PYRIDIN-3-YLOXY)-ACETICACID;Acetic acid, (3-pyridinyloxy)-;3-Pyridyloxyaceticacid;methylindoline-5-carboxylate;SCHEMBL2009003;2-(3-Pyridinyloxy)-acetic acid;DTXSID90390205;2-(Pyridine-3-yl)oxyacetic acid;MBEPWLCDXKKANL-UHFFFAOYSA-N;3-Pyridyloxyacetic acid, AldrichCPR;BBL009657;STK796794;AKOS000285749;SB39170;CS-10152;SY110065;BB 0256753;CS-0156811;FT-0677714;D82223;EN300-147270;F2191-0101

Chemical Property of (Pyridin-3-yloxy)-acetic acid

Chemical Property:

• Vapor Pressure: 0.000219mmHg at 25°C
• Melting Point: 210-212 °C
• Refractive Index: 1.544
• Boiling Point: 312.9 °C at 760 mmHg
• PKA: 2.56±0.10(Predicted)
• Flash Point: 143 °C
• PSA: 59.42000
• Density: 1.3 g/cm³
• LogP: 0.54500
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: Slightly Soluble in water (2.0 g/L)
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 153.042593085
• Heavy Atom Count: 11
• Complexity: 138

Purity/Quality:

99.0%Min ^*data from raw suppliers

(pyridin-3-yloxy)-aceticacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38-22
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CN=C1)OCC(=O)O
• Uses: 3-Pyridyloxyacetic acid is used in synthesis of raw material for fine chemicals, organic intermediate, pharmaceutical intermediate.

Technology Process of (Pyridin-3-yloxy)-acetic acid

There total 3 articles about (Pyridin-3-yloxy)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(pyridin-3-yloxy)acetic acid tert-butyl ester → (Pyridin-3-yloxy)-acetic acid (86649-57-2)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h;

Reference yield:

methyl 2-(pyridin-3-yloxy)-acetate (119967-48-5) → (Pyridin-3-yloxy)-acetic acid (86649-57-2)

Guidance literature:

With sodium hydroxide; In methanol; at 60 ℃; for 2h;

Reference yield:

3-HYDROXYPYRIDINE (109-00-2) + chloroacetic acid (79-11-8) → (Pyridin-3-yloxy)-acetic acid (86649-57-2)

Guidance literature:

With sodium hydroxide; water;

upstream raw materials:

3-HYDROXYPYRIDINE

chloroacetic acid

methyl 2-(pyridin-3-yloxy)-acetate

Downstream raw materials:

2-hydroxy-2-methyl-N-[2-[2-(3-pyridyloxy)acetyl]-3,4-dihydro-1H-isoquinolin-6-yl]propane-1-sulfonamide

6-(4-fluorophenyl)-3-((pyridin-3-yloxy)methyl)[1,2,4]triazolo[4,3-b][1,2,4]triazine

Refernces

• 1、 -. "Phenylazole compounds, process for producing the same and drugs for hyperlipemia". Example 6. . Retrieved 2008/06/13.