2-INDANCARBOXYLIC ACID

Base Information

• Chemical Name: 2-INDANCARBOXYLIC ACID
• CAS No.: 25177-85-9
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Hs Code.: 29163990
• Mol file: 25177-85-9.mol

Synonyms:2-Indancarboxylicacid (6CI,7CI,8CI);2-Indanylcarboxylic acid;Hydrindene-2-carboxylic acid;

Chemical Property of 2-INDANCARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 9.04E-05mmHg at 25°C
• Melting Point: 128-132 °C(lit.)
• Refractive Index: 1.596
• Boiling Point: 326 °C at 760 mmHg
• PKA: 4.65±0.20(Predicted)
• Flash Point: 147.7 °C
• PSA: 37.30000
• Density: 1.24 g/cm³
• LogP: 1.48600
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Indanecarboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-INDANCARBOXYLIC ACID

There total 3 articles about 2-INDANCARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + 1-indene (95-13-6) → Indan-1-carboxylic acid (14381-42-1) + 2-indancarboxylic acid (25177-85-9)

Guidance literature:

1-indene; With 9-borabicyclo[3.3.1]nonane dimer; In 1,2-dimethoxyethane; at 70 ℃; for 24h;

carbon dioxide; With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper(I) iodide; cesium fluoride; In 1,2-dimethoxyethane; at 120 ℃; for 24h;

DOI:10.1039/c9sc02467k

Reference yield:

→ 2-indancarboxylic acid (25177-85-9) + 1-(2,3-dihydro-1H-inden-2-yl)ethanone (33982-85-3)

Guidance literature:

With barium dihydroxide;

Reference yield:

ethyl 2-acetyl-2,3-dihydro-1H-indene-2-carboxylate (86737-24-8) → 2-indancarboxylic acid (25177-85-9) + 1-(2,3-dihydro-1H-inden-2-yl)ethanone (33982-85-3)

Guidance literature:

upstream raw materials:

ethyl 2-acetyl-2,3-dihydro-1H-indene-2-carboxylate

carbon dioxide

1-indene

Downstream raw materials:

indene-2-carboxylic acid

2,3-dihydro-1H-indene-2-carbonyl chloride

phthalonic acid

benzene-1,2-dicarboxylic acid

Refernces