2-(1'-hydroxycyclopentyl)-2-phenylsulphonyloxirane

Base Information

• Chemical Name: 2-(1'-hydroxycyclopentyl)-2-phenylsulphonyloxirane
• CAS No.: 134524-39-3
• Molecular Formula: C₁₃H₁₆O₄S
• Molecular Weight: 268.334
• Mol file: 134524-39-3.mol

Synonyms:2-(1'-hydroxycyclopentyl)-2-phenylsulphonyloxirane

Chemical Property of 2-(1'-hydroxycyclopentyl)-2-phenylsulphonyloxirane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(1'-hydroxycyclopentyl)-2-phenylsulphonyloxirane

There total 1 articles about 2-(1'-hydroxycyclopentyl)-2-phenylsulphonyloxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2-(phenylsulfonyl)oxirane (111832-37-2) + cyclopentanone (120-92-3) → 2-(1'-hydroxycyclopentyl)-2-phenylsulphonyloxirane (134524-39-3)

Guidance literature:

With n-butyllithium; magnesium bromide; In tetrahydrofuran; diethyl ether; toluene; at -102 - -55 ℃;

DOI:10.1039/c39880000645

Reference yield: 80.0%

2-(1'-hydroxycyclopentyl)-2-phenylsulphonyloxirane (134524-39-3) → 1-(bromoacetyl)cyclopentanol (116633-22-8)

Guidance literature:

With magnesium bromide; In diethyl ether; for 2h; Ambient temperature;

upstream raw materials:

2-(phenylsulfonyl)oxirane

cyclopentanone

Downstream raw materials:

1-(bromoacetyl)cyclopentanol

Refernces

• 1、 Ashwell, Mark,Jackson, Richard F. W.. "Phenylsulphonyl Oxirane: a Versatile Reagent for Organic Synthesis". . p. 645 - 647. Retrieved 2007/10/02.