4-CYANOISOXAZOLE

Base Information

• Chemical Name: 4-CYANOISOXAZOLE
• CAS No.: 68776-58-9
• Molecular Formula: C₄H₂N₂O
• Molecular Weight: 94.0727
• Hs Code.: 2934999090
• Mol file: 68776-58-9.mol

Synonyms:4-Cyanoisoxazole;1,2-Oxazole-4-carbonitrile;Isoxazole-4-carbonitrile;

Chemical Property of 4-CYANOISOXAZOLE

Chemical Property:

• Refractive Index: 1.49
• Boiling Point: 226.841 °C at 760 mmHg
• Flash Point: 90.99 °C
• PSA: 49.82000
• Density: 1.258 g/cm³
• LogP: 0.54628
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

Isoxazole-4-carbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CYANOISOXAZOLE

There total 1 articles about 4-CYANOISOXAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-Isoxazole carbaldehyde oxime (6436-76-6) → 4-Cyanoisoxazole (68776-58-9)

Guidance literature:

With thionyl chloride; In dichloromethane; at 45 ℃; for 12h;

Reference yield:

ethanol (64-17-5) + 4-Cyanoisoxazole (68776-58-9) → ethyl isoxazole-4-carboxylate (80370-40-7)

Guidance literature:

With hydrogenchloride; water; Yield given. Multistep reaction; 1.) CHCl₃, 0 deg C, 1 h, 2.) 0 deg C to room temp., 1 h;

upstream raw materials:

4-Isoxazole carbaldehyde oxime

Downstream raw materials:

ethyl isoxazole-4-carboxylate

Refernces