2,2'-BIS(2-CHLOROPHENYL)-4,4',5,5'-TETRAPHENYL-1,2'-BIIMIDAZOLE

Base Information

• Chemical Name: 2,2'-BIS(2-CHLOROPHENYL)-4,4',5,5'-TETRAPHENYL-1,2'-BIIMIDAZOLE
• CAS No.: 6143-80-2
• Molecular Formula: C₂₁H₁₅ClN₂
• Molecular Weight: 330.816
• Mol file: 6143-80-2.mol

Synonyms:Imidazole,2-(o-chlorophenyl)-4,5-diphenyl-, dimer (7CI,8CI);2-o-Chlorophenyl-4,5-diphenylimidazole dimer;

Chemical Property of 2,2'-BIS(2-CHLOROPHENYL)-4,4',5,5'-TETRAPHENYL-1,2'-BIIMIDAZOLE

Chemical Property:

• Boiling Point: 810.3 °C at 760 mmHg
• Flash Point: 443.9 °C
• PSA: 42.54000
• Density: 1.24 g/cm³
• LogP: 9.71290

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2'-BIS(2-CHLOROPHENYL)-4,4',5,5'-TETRAPHENYL-1,2'-BIIMIDAZOLE

There total 11 articles about 2,2'-BIS(2-CHLOROPHENYL)-4,4',5,5'-TETRAPHENYL-1,2'-BIIMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-chloro-benzaldehyde (89-98-5) + benzil (134-81-6) → 2-(2-chlorophenyl)-4,5-diphenyl-1H-imidazole (1707-67-1,6143-80-2)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; 1,1,1,3,3,3-hexamethyl-disilazane; In neat (no solvent); at 150 ℃; for 0.5h; Microwave irradiation;

DOI:10.1039/d1ra05802a

Reference yield: 96.0%

2-chloro-benzaldehyde (89-98-5) + 2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) → 2-(2-chlorophenyl)-4,5-diphenyl-1H-imidazole (1707-67-1,6143-80-2)

Guidance literature:

With ammonium acetate; 1-butylimidazolium tetrafluoroborate; at 100 ℃; for 1.16667h;

DOI:10.1016/j.tet.2005.01.116

Reference yield: 93.0%

ammonium acetate (631-61-8,92206-38-7) + 2-chloro-benzaldehyde (89-98-5) + benzil (134-81-6) → 2-(2-chlorophenyl)-4,5-diphenyl-1H-imidazole (1707-67-1,6143-80-2)

Guidance literature:

With molybdenum oxide supported on silica; In acetonitrile; at 80 ℃; for 3h;

DOI:10.1080/00397911003644415

upstream raw materials:

2-chloro-benzaldehyde

benzil

2-hydroxy-2-phenylacetophenone

ammonium acetate

Refernces

• 1、 Asressu, Kesatebrhan Haile,Chan, Chieh-Kai,Wang, Cheng-Chung. "TMSOTf-catalyzed synthesis of trisubstituted imidazoles using hexamethyldisilazane as a nitrogen source under neat and microwave irradiation conditions". . p. 28061 - 28071. Retrieved 2021/09/15.
• 2、 Hosseini Mohtasham, Nina,Gholizadeh, Mostafa. "Magnetic horsetail plant ash (Fe3O4@HA): a novel, natural and highly efficient heterogeneous nanocatalyst for the green synthesis of 2,4,5-trisubstituted imidazoles". . p. 2507 - 2525. Retrieved 2021/03/24.