L-Alanine-2,3,3,3-d4

Base Information

• Chemical Name: L-Alanine-2,3,3,3-d4
• CAS No.: 18806-29-6
• Molecular Formula: C₃H₇NO₂
• Molecular Weight: 93.0623
• Mol file: 18806-29-6.mol

Synonyms:Alanine-2,3,3,3-d4,L- (7CI,8CI)

Chemical Property of L-Alanine-2,3,3,3-d4

Chemical Property:

• Melting Point: 314.5 °C (dec.)(lit.)
• PSA: 63.32000
• LogP: 0.11850
• Storage Temp.: Refrigerator
• Solubility.: Aqueous Acid (Slightly), Methanol (Slightly), Water (Sparingly)

Purity/Quality:

99% ^*data from raw suppliers

L-Alanine-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-Alanine-d4 is used to make in-vivo measurement of glucose and alanine metabolism in studies of patients with diabetes. L-Alanine is a non-essential amino acid for human development. L-Alanine-d4 is one of the 20 amino acids encoded by the genetic code.

Technology Process of L-Alanine-2,3,3,3-d4

There total 1 articles about L-Alanine-2,3,3,3-d4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-alanin (56-41-7,25191-17-7,18875-37-1) → L-alanine-d4 (18806-29-6,53795-94-1)

Guidance literature:

With α-ketoglutaric acid; water-d2; unter Zusatz von einem Enzym-Praeparat aus Schweine-Herz bei pH 7 und anschliessendes Behandeln mit H₂O;

DOI:10.1093/oxfordjournals.jbchem.a126971

Reference yield:

L-alanine-d4 (18806-29-6,53795-94-1) → L-alanine-d7 (53795-94-1,74280-71-0)

Guidance literature:

With water-d2; recrystallization;

DOI:10.1016/0022-2860(80)85305-1

upstream raw materials:

L-alanin

Downstream raw materials:

L-alanine-d₇

Refernces

• 1、 Gao, Yu,Kodadek, Thomas. "Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides". . p. 360 - 369. Retrieved 2013/06/05.