2-METHOXYTHIAZOLE

Base Information

• Chemical Name: 2-METHOXYTHIAZOLE
• CAS No.: 14542-13-3
• Molecular Formula: C4H5NOS
• Molecular Weight: 115.156
• Hs Code.: 29341000
• Mol file: 14542-13-3.mol

Synonyms:2-methoxy-1,3-thiazole;

Chemical Property of 2-METHOXYTHIAZOLE

Chemical Property:

• Appearance/Colour: Pale yellow clear liquid
• Vapor Pressure: 5.29mmHg at 25°C
• Refractive Index: n20/D 1.5150(lit.)
• Boiling Point: 148.7 °C at 760 mmHg
• PKA: 3.24±0.10(Predicted)
• Flash Point: 43.7 °C
• PSA: 50.36000
• Density: 1.197 g/cm³
• LogP: 1.15170
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2-Methoxythiazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10:
• Hazard Codes: R10:
• Statements: 10
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHOXYTHIAZOLE

There total 9 articles about 2-METHOXYTHIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-1,3-thiazole (3034-53-5,215777-74-5) → 2-methoxythiazole (14542-13-3)

Guidance literature:

With sodium methylate;

DOI:10.1002/hlca.19540370717

Reference yield:

2-chlorothiazole (3034-52-4) → 2-methoxythiazole (14542-13-3)

Guidance literature:

With sodium methylate;

DOI:10.1002/hlca.19540370717

Reference yield:

1,2-dichloro-2-ethoxyethane (623-46-1) + O-methyl thiocarbamate (683-63-6) → 2-methoxythiazole (14542-13-3)

Guidance literature:

With sodium acetate;

upstream raw materials:

diazomethane

3H-thiazol-2-one

2-chlorothiazole

2-bromo-1,3-thiazole

Downstream raw materials:

5-bromo-2-methoxythiazole

4-benzyloxy-2-<(2-methoxythiazol-5-yl)methyl>anisole

5-acetyl-3-methyl-3H-thiazol-2-one

Refernces

• 1、 Cornwell, Stephen P.,Kaye, Perry T.,Kent, Alexander G.,Meakins, G. Denis. "The Structures of 4- and 5-Substituted Δ4-Thiazolin-2-ones". . p. 2340 - 2343. Retrieved 2007/10/02.