DIMETHYL-D6 SULFONE

Base Information

• Chemical Name: DIMETHYL-D6 SULFONE
• CAS No.: 22230-82-6
• Molecular Formula: C2D6O2S
• Molecular Weight: 100.087
• Mol file: 22230-82-6.mol

Synonyms:Methane-d₃, 1,1'-sulfonylbis-;

Chemical Property of DIMETHYL-D6 SULFONE

Chemical Property:

• Vapor Pressure: 0.0573mmHg at 25°C
• Melting Point: 107-109 °C(lit.)
• Refractive Index: 1.402
• Boiling Point: 240.9 °C at 760 mmHg
• Flash Point: 132.7 °C
• PSA: 42.52000
• Density: 1.212 g/cm³
• LogP: 0.74160
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Dimethyl-d6Sulfone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Dimethyl-d6 Sulfone is the labeled analogue of Dimethyl Sulfone (D479350), It can be used as as a high-temperature solvent for both inorganic and organic substances, due to its polarity and thermal stability. It has been also shown to be used for the treatment of Osteoarthritis, in combination with other compounds.

Technology Process of DIMETHYL-D6 SULFONE

There total 3 articles about DIMETHYL-D6 SULFONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.5%

dimethylsulfide (75-18-3) → dimethylsulfone (67-71-0) + ((methyl-d3)sulfonyl)methane-d3 (22230-82-6) + dimethyl sulfoxide (67-68-5,8070-53-9)

Guidance literature:

With <18O,2H6>DMSO; oxygen; methylene blue; In [D₃]acetonitrile; for 0.166667h; Mechanism; Product distribution; Irradiation;

DOI:10.1039/c39830001203

Reference yield: 5.2%

dimethyl sulfide-d6 (926-09-0) → dimethylsulfoxide-d6 (2206-27-1) + ((methyl-d3)sulfonyl)methane-d3 (22230-82-6) + C2H(2)H5O2S

Guidance literature:

With 5,10,15,20-tetrakisphenylporphyrin; oxygen; In benzene; for 1.33333h; Mechanism; Product distribution; Ambient temperature; Irradiation; var. irradiation times, var. solvent, also with addition H₂O; other sulfides; kinetic isotope effect;

DOI:10.1021/ja960323o

Reference yield:

C2H(2)H6OS (103259-34-3) → dimethylsulfoxide-d6 (2206-27-1) + ((methyl-d3)sulfonyl)methane-d3 (22230-82-6) + methyl-d3 peroxy radical + CH(2)H3OS

Guidance literature:

With oxygen; at -23.1 ℃; under 110 Torr; Rate constant; Irradiation;

DOI:10.1021/j100046a024

upstream raw materials:

dimethylsulfide

dimethyl sulfide-d6

C₂H⁽²⁾H₆OS

Downstream raw materials:

dimethyl sulfide-d6

C₁₈H₉⁽²⁾H₆NO₃S

spiroazirine

C₁₈H₉⁽²⁾H₆NO₃S

Refernces

• 1、 Ishiguro, Katsuya,Hayashi, Masaki,Sawaki, Yasuhiko. "Mechanism of sulfone formation in the reaction of sulfides and singlet oxygen: Intermediacy of S-hydroperoxysulfonium ylide". . p. 7265 - 7271. Retrieved 2007/10/03.