3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan

Base Information

• Chemical Name: 3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan
• CAS No.: 4676-33-9
• Molecular Formula: C₂₂H₂₄O₅
• Molecular Weight: 368.43
• Mol file: 4676-33-9.mol

Synonyms:3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan

Chemical Property of 3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan

There total 13 articles about 3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,5-bis-(3,4-dimethoxy-phenyl)-3,4-bis-hydroxymethyl-furan (4687-31-4) → 3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan (4676-33-9)

Guidance literature:

With hydrogen; trimethyleneglycol; In tetrahydrofuran; chloroform; at 80 ℃; for 48h; under 45003.6 Torr;

DOI:10.1080/00397919708006815

Reference yield: 80.0%

1,4-bis(3,4-dimethoxyphenyl),2,3-dimethylbutane-1,4-dione (4440-92-0) → 3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan (4676-33-9)

Guidance literature:

With hydrogenchloride; In methanol; for 1h; Heating;

Reference yield: 45.0%

C22H28O5 → 3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)furan (4676-33-9)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In toluene; at 100 ℃; for 6h;

DOI:10.4067/S0717-97072017000200001

upstream raw materials:

1,4-bis(3,4-dimethoxyphenyl),2,3-dimethylbutane-1,4-dione

(2S*,3S*)-1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane-1,4-dione

2,5-bis-(3,4-dimethoxy-phenyl)-3,4-bis-hydroxymethyl-furan

eudesmin

Downstream raw materials:

terameprocol

all-cis-3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)tetrahydrofuran

1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane

Refernces

• 1、 Macías-Villamizar, Víctor,Cuca-Suárez, Luís. "Structural modification of lignan compounds isolated from Nectandra species (Lauraceae)". . p. 3427 - 3431. Retrieved 2017/08/14.
• 2、 Wu, Anxin,Wang, Mingyi,Pan, Xinfu. "A novel synthetic route to furan-lignans". . p. 2087 - 2091. Retrieved 2007/10/03.