2-Amino-1-(3-chlorophenyl)ethanol hydrochloride

Base Information

• Chemical Name: 2-Amino-1-(3-chlorophenyl)ethanol hydrochloride
• CAS No.: 82171-33-3
• Molecular Formula: C₈H₁₀ClNO*ClH
• Molecular Weight: 208.087
• Hs Code.: 2922199090
• European Community (EC) Number: 850-285-8
• Mol file: 82171-33-3.mol

Synonyms:82171-33-3;2-amino-1-(3-chlorophenyl)ethan-1-ol hydrochloride;2-AMINO-1-(3-CHLOROPHENYL)ETHANOL HYDROCHLORIDE;2-Amino-1-(3-chloro-phenyl)-ethanol HCl;MFCD05861634;2-amino-1-(3-chlorophenyl)ethanol;hydrochloride;2-Amino-1-(3-chlorophenyl)ethanol HCl;(R)-2-AMINO-1-(3-CHLOROPHENYL) ETHANOL HYDROCHLORIDE;2-Amino-1-(3-chloro-phenyl)-ethanol hydrochloride;SCHEMBL2327859;KEYKAIIHCHCFEO-UHFFFAOYSA-N;VT1055;AKOS016011130;SB34178;SB37268;AS-54742;EN300-65277;2-Amino-1-(3-chloro-phenyl)ethanol hydrochloride;A840262;2-Amino-1-(3-chloro-phenyl)-ethanol hydrochloride salt;Benzenemethanol,a-(aminomethyl)-3-chloro-,hydrochloride(1:1)

Chemical Property of 2-Amino-1-(3-chlorophenyl)ethanol hydrochloride

Chemical Property:

• Melting Point: 141 °C(Solv: chloroform (67-66-3))
• Boiling Point: 348.9 °C at 760 mmHg
• Flash Point: 164.8 °C
• PSA: 46.25000
• LogP: 2.83440
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 207.0217694
• Heavy Atom Count: 12
• Complexity: 121

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-1-(3-chloro-phenyl)-ethanolHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)Cl)C(CN)O.Cl

Technology Process of 2-Amino-1-(3-chlorophenyl)ethanol hydrochloride

There total 1 articles about 2-Amino-1-(3-chlorophenyl)ethanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

2-(3-chlorophenyl)-5,5-dimethyl-7,7a-diphenyl-2,3,5,7a-tetrahydroimidazo<5,1-b>oxazole (344584-84-5) → (R)-2-Amino-1-(3-chloro-phenyl)-ethanol; hydrochloride (82171-33-3,169032-01-3)

Guidance literature:

With hydrogenchloride; In dichloromethane; for 24h;

Reference yield:

Methyl-(Z)-6-<(2-endo,3-exo)-3-carboxybicyclo<2.2.1>hept-2-yl>-5-hexenoat (100557-87-7,109667-91-6) + (R)-2-Amino-1-(3-chloro-phenyl)-ethanol; hydrochloride (82171-33-3,169032-01-3) → Methyl-(Z)-6-<(2-endo,3-exo)-3-<<2-(3-chlorphenyl)-2-hydroxyethyl>carbamoyl>bicyclo<2.2.1>hept-2-yl>-5-hexenoat (100557-56-0,109667-96-1,109668-43-1)

Guidance literature:

With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; Yield given. Multistep reaction; 1. THF, 1 h, 0 deg C, 1 h, 20 deg C; 2. THF, 6 h, 20 deg C;

upstream raw materials:

2-(3-chlorophenyl)-5,5-dimethyl-7,7a-diphenyl-2,3,5,7a-tetrahydroimidazo<5,1-b>oxazole

Downstream raw materials:

Methyl-(Z)-6-<(2-endo,3-exo)-3-<<2-(3-chlorphenyl)-2-hydroxyethyl>carbamoyl>bicyclo<2.2.1>hept-2-yl>-5-hexenoat

Refernces