2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL HCL

Base Information

• Chemical Name: 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL HCL
• CAS No.: 849928-38-7
• Molecular Formula: C₈H₁₀FNO*(x)ClH
• Molecular Weight: 191.63
• Mol file: 849928-38-7.mol

Synonyms:Benzenemethanol,a-(aminomethyl)-2-fluoro-,hydrochloride (9CI)

Chemical Property of 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL HCL

Chemical Property:

• PSA: 46.25000
• LogP: 2.32010

Purity/Quality:

99% ^*data from raw suppliers

2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL HCL

There total 1 articles about 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

trimethylsilyl cyanide (7677-24-9) + 2-Fluorobenzaldehyde (446-52-6) → 2-amino-1-(2-fluoro-phenyl)-ethanol hydrochloride (849928-38-7)

Guidance literature:

trimethylsilyl cyanide; 2-Fluorobenzaldehyde; zinc(II) iodide; In dichloromethane; at 20 ℃; for 20h; Inert atmosphere;

With borane-THF; for 5h; Reflux;

With hydrogenchloride; In 1,4-dioxane; methanol; for 2h; Reflux;

upstream raw materials:

trimethylsilyl cyanide

2-Fluorobenzaldehyde

Refernces