7-chloronaphthalene-2-sulfonyl Chloride

Base Information

• Chemical Name: 7-chloronaphthalene-2-sulfonyl Chloride
• CAS No.: 102153-64-0
• Molecular Formula: C10H6 Cl2 O2 S
• Molecular Weight: 261.128
• DSSTox Substance ID: DTXSID90441827
• Nikkaji Number: J469.325F
• Wikidata: Q82258791
• Mol file: 102153-64-0.mol

Synonyms:7-chloronaphthalene-2-sulfonyl Chloride;102153-64-0;7-CHLORO-NAPHTHALENE-2-SULFONYL CHLORIDE;2-Naphthalenesulfonyl chloride, 7-chloro-;SCHEMBL5730048;DTXSID90441827;XZHQZGPVPIOPFH-UHFFFAOYSA-N;GS3179;7-chlornaphthalene-2-sulfonyl chloride;AKOS015911144;2-Naphthalenesulfonylchloride,7-chloro-;FT-0721621

Chemical Property of 7-chloronaphthalene-2-sulfonyl Chloride

Chemical Property:

• PSA: 42.52000
• LogP: 4.50150
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 259.9465560
• Heavy Atom Count: 15
• Complexity: 323

Purity/Quality:

98%min ^*data from raw suppliers

7-CHLORO-NAPHTHALENE-2-SULFONYL CHLORIDE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC2=C1C=CC(=C2)Cl)S(=O)(=O)Cl

Technology Process of 7-chloronaphthalene-2-sulfonyl Chloride

There total 1 articles about 7-chloronaphthalene-2-sulfonyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 7-chloronaphthalene-2-sulfonyl chloride (102153-64-0)

Guidance literature:

With phosphorus pentachloride;

DOI:10.1021/ja01331a037

Reference yield:

phosphorus pentachloride (10026-13-8,874483-75-7) + 7-chloronaphthalene-2-sulfonyl chloride (102153-64-0) → 2,7-dichloronaphthalene (2198-77-8)

Guidance literature:

Reference yield:

7-chloronaphthalene-2-sulfonyl chloride (102153-64-0) → 3-[(S)-3-(7-Chloro-naphthalene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzimidoyl chloride

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 2 h

2: HCl / ethanol / 6 h / 20 °C

With hydrogenchloride; triethylamine; In ethanol; dichloromethane; 1: Condensation / 2: Addition;

DOI:10.1021/jm990040h

Downstream raw materials:

2,7-dichloronaphthalene