1-Methyl-2-(tributylstannyl)pyrrole

Base Information

• Chemical Name: 1-Methyl-2-(tributylstannyl)pyrrole
• CAS No.: 118486-97-8
• Molecular Formula: C17H33NSn
• Molecular Weight: 370.166
• Hs Code.: 29321900
• European Community (EC) Number: 624-775-5
• DSSTox Substance ID: DTXSID00377709
• Mol file: 118486-97-8.mol

Synonyms:118486-97-8;1-Methyl-2-(tributylstannyl)pyrrole;1-methyl-2-(tributylstannyl)-1h-pyrrole;Tributyl-(1-methylpyrrol-2-yl)stannane;1-methyl-2-tributylstannylpyrrole;1-METHYL-2-(TRI-N-BUTYLSTANNYL)PYRROLE;1H-Pyrrole,1-methyl-2-(tributylstannyl)-;(1-Methylpyrrol-2-yl)tributyltin;C17H33NSn;SCHEMBL203858;Tributylstannyl-1-methylpyrrole;2-tributylstannyl-1-methylpyrrole;DTXSID00377709;DINAKCGOEKXDTP-UHFFFAOYSA-N;2-tributylstarinyl-1-methylpyrrole;2-(Tributylstannyl)-1-methylpyrrole;MFCD01319022;1-methyl-2-tri-n-butylstannylpyrrole;AKOS015843035;N-methyl-2-tributylstannyl-1H-pyrrole;1-methyl-2-tributylstannyl-1H-pyrrole;AB08849;1-Methyl-2-(tributylstannyl)-1H-pyrole;1-methyl-2-tributylstannanyl-1H-pyrrole;n-methyl-2-(tributylstannyl)-1h-pyrrole;1-Methyl-2-(tributylstannyl)pyrrole, 95%;1-n-methyl-2-(tributylstannyl)-1h-pyrrole;FT-0608043;A50078;EN300-730059;J-504908

Chemical Property of 1-Methyl-2-(tributylstannyl)pyrrole

Chemical Property:

• Vapor Pressure: 1.59E-05mmHg at 25°C
• Refractive Index: n20/D 1.5107
• Boiling Point: 376.3 °C at 760 mmHg
• PKA: -2.77±0.70(Predicted)
• Flash Point: 181.4 °C
• PSA: 4.93000
• Density: 1.1223 g/mL at 25 °C
• LogP: 5.08120
• Storage Temp.: ?20°C
• Solubility.: Not miscible or difficult to mix.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 10
• Exact Mass: 371.163503
• Heavy Atom Count: 19
• Complexity: 208

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Methyl-2-(tributylstannyl)-1H-pyrrole ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T, Xi, N
• Hazard Codes: T,Xi,N
• Statements: 21-25-36/38-48/23/25-50/53
• Safety Statements: 26-28-36/37-45-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC[Sn](CCCC)(CCCC)C1=CC=CN1C
• Uses: It is employed as intermediate for pharmaceutical. 1-Methyl-2-(tributylstannyl)pyrrole can be used as a reactant to prepare: Bithienylpyrrole derivatives through a Stille coupling reaction with bithienyl bromides in the presence of Pd catalyst. Di(bisthienyl)-o-carborane (DBTC) by reacting with 5,5′-dibromo-o-carboranyl-bisthiophenes using Pd catalyst. DBTC is electropolymerized to produce conducting polymers. Poly(Py-BTz-Py) (2-butyl-4,7-bis(1-methyl-1H-pyrrol-2-yl)-2H-benzo[d][1,2,3]triazole) via Stille coupling reaction. Poly(Py-BTz-Py) can be used as an organic photocatalyst for the formation C-C bond under visible light irradiation.

Technology Process of 1-Methyl-2-(tributylstannyl)pyrrole

There total 2 articles about 1-Methyl-2-(tributylstannyl)pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-Methylpyrrole (96-54-8) + tributyltin chloride (1461-22-9) → 1-methyl-2-(tributyltin)pyrrole (118486-97-8)

Guidance literature:

N-Methylpyrrole; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 - 20 ℃; for 2h;

tributyltin chloride; In tetrahydrofuran; pentane; at -78 - 20 ℃;

Reference yield:

N-Methylpyrrole (96-54-8) + N,N,N,N,-tetramethylethylenediamine (110-18-9) + tributyltin chloride (1461-22-9) → 1-methyl-2-(tributyltin)pyrrole (118486-97-8)

Guidance literature:

With n-butyllithium; In tetrahydrofuran;

Reference yield: 95.0%

(1S)-1,5-anhydro-2,3,4,6-tetra-O-benzyl-1-[3-(bromomethyl)phenyl]-1-thio-D-glucitol (898538-67-5) + 1-methyl-2-(tributyltin)pyrrole (118486-97-8) → (1S)-1,5-anhydro-2,3,4,6-tetra-O-benzyl-1-[3-[(1-methyl-1H-pyrrol-2-yl)methyl]phenyl]-1-thio-D-glucitol

Guidance literature:

With potassium fluoride; caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; CyJohnPhos; In 1,4-dioxane; at 60 ℃; for 8h;

upstream raw materials:

N-Methylpyrrole

N,N,N,N,-tetramethylethylenediamine

tributyltin chloride

Downstream raw materials:

(6R,7R)-7-tert-Butoxycarbonylamino-3-(1-methyl-1H-pyrrol-2-yl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

acetic acid 1-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-yl ester

1-methyl-2-(2-nitrophenyl)-1H-pyrrole

(1-methyl-1H-pyrrol-2-yl)-(4-nitrophenyl)-methanone

Refernces

• 1、 -. "2-heteroaryl-5,11-dihydro-6H-dipyrido?3,2-B:2',3'-E!?1,4!diazepines and their use in the prevention or treatment of HIV infection". . . Retrieved 2008/06/13.