(+/-)-11-NOR-9-CARBOXY-DELTA9-THC

Base Information

• Chemical Name: (+/-)-11-NOR-9-CARBOXY-DELTA9-THC
• CAS No.: 104874-50-2
• Molecular Formula: C₂₁H₂₈O₄
• Molecular Weight: 344.451
• Mol file: 104874-50-2.mol

Synonyms:6H-Dibenzo[b,d]pyran-9-carboxylicacid, 6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-, trans-(?à)-; (?à)-11-Nor-D9-tetrahydrocannabinol-9-carboxylic acid;6H-Dibenzo[b,d]pyran-9-carboxylic acid,6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-, trans-

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of (+/-)-11-NOR-9-CARBOXY-DELTA9-THC

Chemical Property:

• Melting Point: 174-176 °C
• Boiling Point: 466.9±45.0 °C(Predicted)
• PKA: 4.66±0.40(Predicted)
• Flash Point: 9℃
• PSA: 66.76000
• Density: 1.140±0.06 g/cm3(Predicted)
• LogP: 4.80050
• Storage Temp.: −20°C

Purity/Quality:

Safty Information:

• Pictogram(s): F,T
• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45

MSDS Files:

SDS file from LookChem

Useful:

• Description: (±)-11-nor-9-carboxy-Δ9-THC (CRM) (Item No. 20754) is a certified reference material that is structurally categorized as a cannabinoid metabolite. 11-nor-9-carboxy-Δ9-THC is an abundant secondary metabolite of Δ9-THC (Item Nos. ISO60157 | 12068) and is produced by the oxidation of the primary metabolite 11-hydroxy-Δ9-THC. This product is intended for research and forensic applications.

Technology Process of (+/-)-11-NOR-9-CARBOXY-DELTA9-THC

There total 32 articles about (+/-)-11-NOR-9-CARBOXY-DELTA9-THC which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(+/-)-11-nor-9-carboxy-Δ9-tetrahydrocannabinol tert-butyldimethylsilyl ether (138176-22-4,138285-38-8) → (+/-)-11-Nor-9-carboxy-Δ9-tetrahydrocannabinol (104874-50-2)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1.25h; Ambient temperature;

DOI:10.1055/s-1991-26590

Reference yield: 54.0%

carbon dioxide (124-38-9,18923-20-1) + C35H52N2O4S (949595-94-2) → 11-nor-9-carboxt-Δ-9-tetrahydrocannabinol (36557-05-8,56354-06-4,64280-14-4,104874-50-2,114028-39-6,122797-75-5)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; 1.) -78 deg C to 0 deg C, 30 min, 2.) 3 min;

DOI:10.1021/jo970969e

Reference yield: 54.0%

carbon dioxide (124-38-9,18923-20-1) + C35H52N2O4S → (+/-)-11-Nor-9-carboxy-Δ9-tetrahydrocannabinol (104874-50-2)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; 1.) -78 deg C to 0 deg C, 30 min, 2.) 30 s;

DOI:10.1021/jo970969e

upstream raw materials:

1-Methoxymethoxy-6,6-dimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromene-9-carboxylic acid

Acetic acid (6aR,10aR)-9-formyl-6,6-dimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-yl ester

(+/-)-11-nor-9-carboxy-Δ⁹-tetrahydrocannabinol tert-butyldimethylsilyl ether

carbon dioxide

Downstream raw materials:

C₂₅H₃₁NO₆

Refernces

• 1、 -. "TETRAHYDROCANNABINOID ANTIGENS AND METHOD OF USE". Page/Page column Figure 8. . Retrieved 2010/10/20.
• 2、 Huffman, John W.,Zhang, Xuehai,Wu, Ming-Jung,Joyner, H. Howard,Pennington, William T.. "Synthesis of (+/-)-11-Nor-9-carboxy-Δ9-tetrahydrocannabinol: New Synthetic Approaches to Cannabinoids". . p. 1481 - 1489. Retrieved 2007/10/02.