SEC-BUTYLMAGNESIUM CHLORIDE

Base Information

• Chemical Name: SEC-BUTYLMAGNESIUM CHLORIDE
• CAS No.: 15366-08-2
• Molecular Formula: C4H9ClMg
• Molecular Weight: 116.873
• Hs Code.: 29319090
• Mol file: 15366-08-2.mol

Synonyms:Magnesium,sec-butylchloro- (7CI,8CI);2-Butylmagnesium chloride;

Chemical Property of SEC-BUTYLMAGNESIUM CHLORIDE

Chemical Property:

• Appearance/Colour: Light to dark-brown solution
• Boiling Point: 66oC
• Flash Point: -21oC
• PSA: 0.00000
• Density: 0.83 g/mL at 20oC
• LogP: 2.44360
• Storage Temp.: Flammables + water-Freezer (-20°C)e area
• Sensitive.: air sensitive, moisture sensitiv

Purity/Quality:

99% ^*data from raw suppliers

sec-Butylmagnesium chloride, lithium chloride complex 1.2M (15wt% ±1wt%) in tetrahydrofuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F+, C
• Hazard Codes: F+,C,F
• Statements: 12-14/15-22-34-66-67-19-11
• Safety Statements: 16-26-36/37/39-43-45-7/8

MSDS Files:

SDS file from LookChem

Useful:

• Uses: sec-Butylmagnesium chloride solution is a Grignard reagent, it can be used in: Metal catalyzed cross-coupling reactions with non-activated aryl chlorides.The synthesis of various alkoxytrichlorosilanes by reacting with tetrachlorosilane and alcohols.

Technology Process of SEC-BUTYLMAGNESIUM CHLORIDE

There total 5 articles about SEC-BUTYLMAGNESIUM CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

s-butyl chloride (78-86-4,53178-20-4) → s-butylmagnesium chloride (15366-08-2,79722-38-6)

Guidance literature:

With magnesium; In tetrahydrofuran-d8; at 80 ℃; under 5171.62 Torr; Inert atmosphere; Flow reactor;

DOI:10.3762/bjoc.16.115

Reference yield:

s-butyl chloride (78-86-4,53178-20-4) + magnesium (7439-95-4) → s-butylmagnesium chloride (15366-08-2,79722-38-6)

Guidance literature:

In tetrahydrofuran;

Reference yield:

s-butyl chloride (78-86-4,53178-20-4) → 9-(2-butyl)-9,10-dihydroanthracene (10394-54-4) + s-butylmagnesium chloride (15366-08-2,79722-38-6) + 2-(2-butyl)-1,2-dihydroanthracene + 9,10-Di-sec-butyl-9,10-dihydro-anthracene (126694-92-6)

Guidance literature:

With magnesium anthracene * 3 THF; In diethyl ether; for 48h; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

upstream raw materials:

s-butyl chloride

magnesium

Downstream raw materials:

3-methyl-1-pentene

(+/-)-2-Methylheptan-4-ol

3,6-dimethyloctane-4,5-dione

ethyl 4-methyl-2-oxopentanoate

Refernces

• 1、 -. "PROCESS FOR PRODUCING PHOSPHONIUM BORATE COMPOUND, NOVEL PHOSPHONIUM BORATE COMPOUND, AND METHOD OF USING THE SAME". Page/Page column 68-69. . Retrieved 2008/06/13.
• 2、 Bogdanovic, Borislav,Janke, Nikolaus,Kinzelmann, Hans-Georg. "Use of Magnesium Anthracene * 3 THF in Synthesis: Generation of Grignard Compounds and Other Reactions with Organic Halides". . p. 1507 - 1515. Retrieved 2007/10/02.