(S)-3-HYDROXYBUTYRIC ACID SODIUM SALT

Base Information

• Chemical Name: (S)-3-HYDROXYBUTYRIC ACID SODIUM SALT
• CAS No.: 127604-16-4
• Molecular Formula: C4H7NaO3
• Molecular Weight: 126.09
• Hs Code.: 2918199090
• Mol file: 127604-16-4.mol

Synonyms:Butanoicacid, 3-hydroxy-, monosodium salt, (3S)- (9CI);Butanoic acid, 3-hydroxy-,monosodium salt, (S)-;

Chemical Property of (S)-3-HYDROXYBUTYRIC ACID SODIUM SALT

Chemical Property:

• Melting Point: 149-153 °C(lit.)
• PSA: 60.36000
• LogP: -1.49280
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Sodium(S)-3-Hydroxybutyrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-24/25-22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium (S)-3-Hydroxybutyrate is a useful chemical for the preparation of dideoxymycobactin (DDM).

Technology Process of (S)-3-HYDROXYBUTYRIC ACID SODIUM SALT

There total 1 articles about (S)-3-HYDROXYBUTYRIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-3-hydroxybutyric acid methyl ester (53562-86-0) → (S)-(+)-3-hydroxybutyric acid sodium salt (127604-16-4)

Guidance literature:

With sodium hydroxide;

Reference yield: 80.0%

O-benzylhydoxylamine hydrochloride (2687-43-6) + (S)-(+)-3-hydroxybutyric acid sodium salt (127604-16-4) → C11H15NO3 (946853-98-1)

Guidance literature:

With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In tetrahydrofuran; water; at 20 ℃; for 16h;

DOI:10.1016/j.tetlet.2007.05.085

Reference yield:

(S)-(+)-3-hydroxybutyric acid sodium salt (127604-16-4) + tert-butyldimethylsilyl chloride (18162-48-6) → C16H36O3Si2

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 - 75 ℃;

DOI:10.1021/ja068033n

upstream raw materials:

(S)-3-hydroxybutyric acid methyl ester

Downstream raw materials:

C₁₁H₁₅NO₃

Refernces