(R)-(-)-2-Phenylbutyric acid

Base Information Edit

Chemical Name:(R)-(-)-2-Phenylbutyric acid
CAS No.:938-79-4
Molecular Formula:C10H12O2
Molecular Weight:164.204
Hs Code.:29163900
European Community (EC) Number:618-983-5
UNII:1238B41M1H
DSSTox Substance ID:DTXSID50354863
Wikidata:Q27251362
Mol file:938-79-4.mol

Synonyms:(R)-(-)-2-Phenylbutyric acid;938-79-4;(2r)-2-phenylbutanoic acid;(R)-2-phenylbutyric acid;(r)-2-phenylbutanoic acid;2-Phenylbutyric acid, (R)-;(R)-(-)-2-Phenylbutanoic acid;MFCD00063165;1238B41M1H;Butyric acid, 2-phenyl-, (R)-(-)-;Benzeneacetic acid, alpha-ethyl-, (R)-;(r)-2-phenylbutanoicacid;(RS)-2-phenylbutyric acid;SCHEMBL65737;(2R)-2-phenyl-Butanoic Acid;UNII-1238B41M1H;DTXSID50354863;Benzeneacetic acid,a-ethyl-,(ar)-;AKOS015840435;Benzeneacetic acid, a-ethyl-, (aR)-;(R)-(-)-2-Phenylbutyric acid, 99%;AS-43511;BP-12896;Benzeneacetic acid, alpha-ethyl-, (alphaR)-;CS-0204420;BENZENEACETIC ACID, .ALPHA.-ETHYL-, (R)-;Q27251362;BENZENEACETIC ACID, .ALPHA.-ETHYL-, (.ALPHA.R)-

Suppliers and Price of (R)-(-)-2-Phenylbutyric acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(?)-2-Phenylbutyric acid
500mg
$ 50.00

SynQuest Laboratories
(R)-(-)-2-Phenylbutyric acid
5 g
$ 413.00

SynQuest Laboratories
(R)-(-)-2-Phenylbutyric acid
1 g
$ 125.00

Sigma-Aldrich
(R)-(?)-2-Phenylbutyric acid 99%
1g
$ 98.90

Medical Isotopes, Inc.
(R)-(?)-2-Phenylbutyric acid
1 g
$ 650.00

Crysdot
(R)-2-Phenylbutanoicacid 97%
1g
$ 160.00

Apolloscientific
(R)-(?)-2-Phenylbutyric acid
1g
$ 114.00

Apolloscientific
(R)-(?)-2-Phenylbutyric acid
5g
$ 375.00

American Custom Chemicals Corporation
(R)-(-)-2-PHENYL BUTYRIC ACID 95.00%
10G
$ 1725.32

American Custom Chemicals Corporation
(R)-(-)-2-PHENYL BUTYRIC ACID 95.00%
1G
$ 690.18

Total 29 raw suppliers

Chemical Property of (R)-(-)-2-Phenylbutyric acid Edit

Chemical Property:

Appearance/Colour:clear colorless liquid
Vapor Pressure:0.00288mmHg at 25°C
Refractive Index:n20/D 1.516
Boiling Point:272.9 °C at 760 mmHg
Flash Point:170.2 °C
PSA：37.30000
Density:1.09 g/cm³
LogP:2.26480
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Ethanol (Slightly), Toluene (Slightly)
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:164.083729621
Heavy Atom Count:12
Complexity:148

Purity/Quality:

98%,99%, ^*data from raw suppliers

(R)-(?)-2-Phenylbutyric acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22
Safety Statements: 23-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1=CC=CC=C1)C(=O)O
Isomeric SMILES:CC[C@H](C1=CC=CC=C1)C(=O)O
Uses (R)-(-)-2-Phenylbutyric Acid, is the metabolite of Butamirate (B690025), which is a novel antitussive drug.

Technology Process of (R)-(-)-2-Phenylbutyric acid

There total 56 articles about (R)-(-)-2-Phenylbutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 27854-88-2,42732-22-9
(R)-1-(4-pyridinyl)ethanol

: 90-27-7
2-Phenylbutyric acid

: 4286-15-1
(S)-2-phenylbutyric acid

: 938-79-4
(2R)-2-phenylbutanoic acid

: 88549-64-8,88549-65-9,88588-27-6,88588-31-2,97996-71-9,134624-71-8
2-Phenyl-butyric acid (R)-1-pyridin-4-yl-ethyl ester

Guidance literature:: With Palomo reagent; triethylamine; In toluene; for 48h; Yields of byproduct given; Ambient temperature;
DOI:10.1016/0957-4166(92)80022-O